there actually has been several accounts of it happening.
a really popular grower by the name of Phillthy had a plant that flowered female, then on the second run it flowered male and become one of his staple breeding plants. I have had a plant that preflowered male, for the first few weeks of 12/12 then after removing the males parts she flowered female and clone generations after never showed the intersex...
hence my ethylene/maturity hypothesis.
hemp is weird some times.