Im NOT saying you have to change your Ideology thats yours... But im saying your Lines will probably become weak with the Years. Just my Analysis, not saying anything.
Sure, that's why i'm glad knowing Rahan is a biologist with enough knowledge on plant genetics, and year after year kept reproducing batches of seeds from the original thousands from his first open pollination, in order to avoid the issues and genetic drift from small populations. 50 plants x 10 times means 500 plants. Not the same as 1000 but probably getting closer to a perfect enough population with the time.
I also keep enough frozen seeds from a refreshing reproduction done by a friend and talented grower under tropical sun in the right latitude and environmental conditions, for long term and future in-situ genetic conservation.
So don't worry, the most important work has been done already by some people, especially knowing there are hundreds of cultivars getting extinct by now. Doing indoor dozen plant repros one after the other is just producing even more inbreeding and doing more harm than good to the cultivar's genepool really. Reproduce, storage right and move on to the next one is what Cannabis really needs, if the goal is preserving genetics rather than egos.