The Terpenes of Cannabis Their Aromas and Effects

[hydr1]

Go on...

 

[Bubbleblower]

Go on...

What if Sugar Magnolia was about Sugar Magnolia?

 

[Hydrosun]

Tag. Epic post.

yep, this is now bookmarked.

 

[Daub Marley]

^^^
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Very interesting, great post Daub!

I wasn't aware of pyrazine; what's intriguing about the concept of oxidized terpenes is that I noticed a few months back when my dog was sprayed by a skunk that the initial spray does not resemble what we all commonly refer to as the 'Roadkill skunk' smell. It's predominantly sulfur smelling, like burnt rubber. Nasty, putrid funk.

The next day, though, the patio area and the room she first came into smelled like someone smoked some killer skunk bud. So it took some time for the initial sulfur smell to sort of mature into a different aroma entirely, to what we identify as roadkill skunk.

I was just reading today how isoamyl acetate (the banana smell) will start to smell like pears when it's diluted enough, so that effect could also play a role in skunk spray because I've noticed that also. We are unimaginably sensitive to the smell of certain chemicals and they will overpower the other scents.

I have almost never found bud that actually smells roadkill in the bag. Only after it was smoked did the room have that skunk funk. Interesting to think that it could be initial terpenes + oxidation that creates that roadkill funk. The odd thing is Skunkman and some people's recollection of bud that smelled like roadkill, something I haven't personally experienced, but would suggest there are/were ("what happened to RKS?") terpenes capable of producing that smell on their own.

Oh its definitely out there. It was really popular in the 90's and my brother got his hands on a few bags before it went out. It would smell up the room through multiple bags and through a safe. Not even any touching or any agitation of any kind. I am flowering some BC skunk from Cannacopia, but I just started them. I hope I get a super skunky smelling pheno! There used to be a Durban Poison cut that smelled like a skunky coffee scent and I would give my left nut for it now.

 

[RonSmooth]

The article would better without the tendentious generalizations. It really damages the credibility of an otherwise well put together piece.

 

[Hydrosun]

We do respect copyright law here at ICMag... it is for the common good.

There has ALWAYS been an exception to copyright for scholarly research. So long as we are not reselling someone else's work, ALL scientific discovers are public domain for repetition of the experiment and for additive work.

So anyone posting PDFs to this site for education and discussion purposes is doing a service to mankind. If authors, inventors, or scientists want their work to be private they are free not to publish. If they publish their work is subject to public scrutiny from armature scientists like us, and professionals as well.

 

[G.O. Joe]

I have almost never found bud that actually smells roadkill

It never smelled like roadkill, that's just when people would usually encounter skunk odor, until 10-20 years ago when most all the commercial baggage around here was more or less skunky. Nonsmokers could tell if you had a couple grams of medium-stench grade on you from a distance, in a baggie or even a film canister. As Daub says any relation of BO (bud odor) to any thiols or thiol bio-precursors is unknown.

There has ALWAYS been an exception to copyright for scholarly research.

This is a commercial site.

How would Mark Twain summarize this thread?

Here another recent example for the RKS fans:

Workers die after chemical leak at DuPont plant near Houston (Reuters).

Mercaptan is very deadly and very bad for your eyes.

To my knowledge the skunk smell from cannabis is not mercaptans.

we are getting trace amounts of this chemical when vaping.

I like science because it gives one such a wholesome return of conjecture from such a trifling investment of fact.

 

[Bubbleblower]

The smell I am referring to is specifically skunk, thiols.
Like they used to have in California in the 80's.
In Europe the pheno was never found afaik.
Back then I didn't understand why I needed Visine in the States and not in Europe.

I wonder why the RKS pheno was found in northern California but never in southern California (could that be because there doesn't grow skunk cabbage south of Sta. Cruz?) and why nobody has ever managed to recreate it; RKS fan club thread

Male mice use thiols in their urine "activating certain mouse olfactory sensory neurons, attracting female mice".
Interestingly women emit a lot of it too, which could explain why so many people like it, despite the repulsive smell.

 

[Daub Marley]

The smell I am referring to is specifically skunk, thiols.
Like they used to have in California in the 80's.
In Europe the pheno was never found afaik.
Back then I didn't understand why I needed Visine in the States and not in Europe.

The thing is that the chemical that smells like thiols in cannabis probably isn't actually thiols. Our nose can trick us with certain chemicals because they might have the same shape or vibrational frequency as other known and familar chemicals and so our nose fools our brains into thinking the two different chemicals are the same. So two different chemicals can smell identical if certain criteria are met.

I wonder why the RKS pheno was found in northern California but never in southern California (could that be because there doesn't grow skunk cabbage south of Sta. Cruz?) and why nobody has ever managed to recreate it; RKS fan club thread

People liked to smoke it, but not to grow it. It would smell 10x stronger than any fruity smelling strain, and alert anyone in like a 1/4 mile radius.

Male mice use thiols in their urine "activating certain mouse olfactory sensory neurons, attracting female mice".
Interestingly women emit a lot of it too, which could explain why so many people like it, despite the repulsive smell.

Everything that makes this plant special is how it defends itself from the outside world. It wouldn't be unreasonable to assume that the thiol-like smell is produced by the plant in an attempt to mimic a predators urine.
While I'm sure there are foul smelling skunk strains I have never experienced it. Everyone enjoys the smell of coffee but it has thiols in it. I think people like it simply because it smells good (its not conditioned), but the reason that coffee smells good to us as humans IS probably some evolutionary leftover that was once used by our ancestors for things like sex or territorial marking.

 

[nattynattygurrl]

"CBG (Cannabigerol) Antimicrobial, Anti-proliferative, Bone stimulant”…

I hate to ask, I hope you will please forgive me if this is posted somewhere or is a stupid question, (I have long been absent and am playing catchup), would anyone happen to have a strain name, off the top of there head, that has tested high in CBG?


Anyone who could point me in the direction of a CBG strain, my bones and I would forever in your debt!

 

[Only Ornamental]

...
Anyone who could point me in the direction of a CBG strain, my bones and I would forever in your debt!

Bernabeo, an Italian hemp variety currently only used for breeding purposes (likely, this variety or crosses thereof will be registered in the future). You might be able to get it at the Italian institute for hemp crop breeding. You find a publication with their address in the header HERE.
Furthermore, I recently saw a post here on board of a cannabinoid profile of a variety extremely high in CBG IIRC.

Now that your in my debt, can I trade it for something?

Besides, CBD affects osteoclasts via GPR55 inhibition and THC is likely to affect osteoclasts and osteoblasts. Bad thing is, that bones aren't that simple and the effect on them mediated by cannabinoids also depend on developmental state (age) and disease. AFAIK there's no conclusive study available regarding this subject. Here four review articles on that subject CLICK, CLACK, CLOCK and CLONK.
If cannabigerol helps, I do know know... this compound shows a bunch of other activities as well. Remains to be seen what the net effect in vivo turns out to be...

 

[nattynattygurrl]

You sir, are a gentleman and a scholar!!
Thank you Only Ornamental for taking the time to help me! I owe you big time!!

I’m gonna go try to read the articles you posted and hopefully, go save the rest/what’s left of my bones!!

 

[BananaHammock]

Fantastic post. This is being printed out and put on the door to my room.

 

[tea_is_back]

thx for this great info thread

 

[EclipseFour20]

Now if we could only "reverse engineer" this....that is, determine what/how to modify the emission rate of a particular terpene. Example, certain terpene emission rates increase when a given plant is under abiotic stress (water deficit, temperature extreme, environment, etc) and/or biotic stress (fungi, bacteria, insects, viruses, etc).

Is it that simple?--"starve the plant" or "stick a thumbtack in the stalk just above the soil line" or "infect it with a particular fungi/bacteria".....and the plant's terpene emission rate is modified....LOL--wives tale, fable or secret? Wondering minds....

 

[Hydrosun]

Now if we could only "reverse engineer" this....that is, determine what/how to modify the emission rate of a particular terpene. Example, certain terpene emission rates increase when a given plant is under abiotic stress (water deficit, temperature extreme, environment, etc) and/or biotic stress (fungi, bacteria, insects, viruses, etc).

Is it that simple?--"starve the plant" or "stick a thumbtack in the stalk just above the soil line" or "infect it with a particular fungi/bacteria".....and the plant's terpene emission rate is modified....LOL--wives tale, fable or secret? Wondering minds....

Inject the fungi that causes it to host truffles in its root system please. We need that in every 200 gallon smart pot in CA!!!!

 

[TheMedicalStone]

Besides, CBD affects osteoclasts via GPR55 inhibition and THC is likely to affect osteoclasts and osteoblasts. Bad thing is, that bones aren't that simple and the effect on them mediated by cannabinoids also depend on developmental state (age) and disease. AFAIK there's no conclusive study available regarding this subject. Here four review articles on that subject CLICK, CLACK, CLOCK and CLONK.
If cannabigerol helps, I do know know... this compound shows a bunch of other activities as well. Remains to be seen what the net effect in vivo turns out to be...

Just finished reading all of them. It's not really that negative if you ask me. They notice significant increase in mouse models even with just testing 2 compounds while leaving out all the others which could either work benefitial or negative but still. It still looks fairly promising in mouse models IMO. Plus the studies are fairly old, they are most likely working on it still. No news is generally good news if it comes to a "hype product" (which CBD happens to be right now) so, as they stated themselfs, they pretty much don't know the effect of some agents yet and in some of the researches I might even say it goes far that they dared to label somethings as "good" or "bad" already (aimed at skeletal development of unborn mice in this case) until full research is done but still, pretty promising if you read between the lines a bit and connect the dots . Ofcourse, all might fail in vivo or even before that stage as most promising cures/treatments do lol but still, even for bone issues I'm fairly excited.

 

[mexcurandero420]

Well take also a look to Royal Jelly

Royal Jelly Prevents Osteoporosis in Rats

Keep on growing

 

[TheMedicalStone]

Well take also a look to Royal Jelly

Royal Jelly Prevents Osteoporosis in Rats

Keep on growing

Knew that

Certain bee poison seems to help against cancer. So does scorpion poison (actual treatment in cuba, saved a terminal patient I know 's life, twice actually), poison from a subspecies of a (strawberry) Pumilio poison dart frog is actually used as a great Anesthetic for surgery and such in the area it's from.

The natural world is full of wonders ^_^ some we know about, some we have yet to learn about and some are, unfortunately, just chosen to ignore.

 

[Daub Marley]

Now if we could only "reverse engineer" this....that is, determine what/how to modify the emission rate of a particular terpene. Example, certain terpene emission rates increase when a given plant is under abiotic stress (water deficit, temperature extreme, environment, etc) and/or biotic stress (fungi, bacteria, insects, viruses, etc).

Is it that simple?--"starve the plant" or "stick a thumbtack in the stalk just above the soil line" or "infect it with a particular fungi/bacteria".....and the plant's terpene emission rate is modified....LOL--wives tale, fable or secret? Wondering minds....

Sure it would. How and to what extent is unknown.