Belgians?
vlamser frittes are pretty good too...and they produce a lot of good bike racers...but still....belgians
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Covid 19 mrna Vaccines...Yes/No?
- Thread starter gaiusmarius
- Start date
vlamser frittes are pretty good too...and they produce a lot of good bike racers...but still....belgians
what a vaxxhat!
not if they still let belgians in
got something against Walloons, eh? they make the French fops look masculine, lol...
i guess no one here has read the hitchhikers guide to the galaxy books, "belgium" is the third most insulting word in the galaxy
unless you are from New Zealand. try calling one of those ol' boys an "aussie" some time, lol...
i worked in a fancy kitchen with a chef from new zealand,i liked to call him an australian wetback,which really pissed him off,and i suppose is enough to get me cancelled these days,good thing i'm not famous
troutman
Seed Whore
Get a shot, get a gun
Nigerian Study Shows The Use of Ivermectin Alone in Treating COVID-19 as Effective as Hydroxychloroquine, Azithromycin, and Ivermectin Combination
By Jim Hoft
Published October 5, 2021 at 7:00am
163 Comments
Photo by Soumyabrata NURPHOTO VIA GETTY IMAGES
A recent study in Nigeria shows that using Ivermectin-only (IVM) to treat COVID-19 patients is equally as effective as using the HIA triple therapy (Hydroxychloroquine, Ivermectin, and Azithromycin Combination) in all inflammatory, virological, and respiratory endpoints.
This study was set up to compare Ivermectin with Ivermectin plus HCQ+IVM (HIA) treatment.
The study design was a single-blind, randomized, parallel-group study of 2 groups of COVID-19-positive Nigerian patients with 30/31 subjects in each treatment arm.
Thirty patients received ivermectin 200 mcg/kg daily for five days and thirty-one patients received HIA triple therapy. What referred to us HIA triple therapy is the use of Hydroxychloroquine 200mg per day for three days, Ivermectin 200mcg/kg daily for five days, Azithromycin 500mg per day for three days. None of the patients had been vaccinated.
This was a relatively small sample size but it found that both therapies showed significant reductions in inflammation.
Here’s an excerpt from the study:
DISCUSSION:
Here are some of the questions that were answered by the researchers:
Questions: There was no control group with no treatment, so how do you know that ivermectin was better than no treatment?
Answer: This is a follow-on paper of a previous publication in which we had demonstrated the superiority if ivermectin relative to control. Babalola OE, Bode CO, Ajayi AA, Alakaloko FM, Akase IE, Otrofanowei E, Salu OB, Adeyemo WL, Ademuyiwa AO, Omilabu S. Ivermectin shows clinical benets in mild to moderate COVID19: a randomized controlled double-blind, dose-response study in Lagos, QJM: An International Journal of Medicine, 2021;, hcab035, https://doi.org/10.1093/qjmed/hcab035 Besides, our hypothesis was to test if the addition of HCQ and AZM would increase the therapeutic effect. In the event, it did not appear to do so.
In addition to the aforesaid, regarding our previous double blinded RCT which demonstrated the significant dose-dependent SARS-COV-2 virucidal efficacy of ivermectin, we were ethically constrained, not to deprive any treatment arm and patients, a medication for a potentially fatal disease, which we have shown to be beneficial. No Institutional Review Board would grant approval for such a study on ethical grounds of with holding a therapy. that may be beneficial. just for scientific elegance.
Question:Why is there no control in this work?
Answer: We are not comparing ivermectin with no treatment. We are comparing ivermectin with Ivermectin plus HCQ+IVM (HIA). The work comparing ivermectin with control has already been done and published. It shows a hazard ratio of 2.0 compared to control with regards to viral clearance. (Babalola et al 2021). The hypothesis been tested here is IVM versus HIA.
You can read the full study here: https://www.researchsquare.com/article/rs-950352/v1
By Jim Hoft
Published October 5, 2021 at 7:00am
163 Comments
Photo by Soumyabrata NURPHOTO VIA GETTY IMAGES
A recent study in Nigeria shows that using Ivermectin-only (IVM) to treat COVID-19 patients is equally as effective as using the HIA triple therapy (Hydroxychloroquine, Ivermectin, and Azithromycin Combination) in all inflammatory, virological, and respiratory endpoints.
This study was set up to compare Ivermectin with Ivermectin plus HCQ+IVM (HIA) treatment.
The study design was a single-blind, randomized, parallel-group study of 2 groups of COVID-19-positive Nigerian patients with 30/31 subjects in each treatment arm.
Thirty patients received ivermectin 200 mcg/kg daily for five days and thirty-one patients received HIA triple therapy. What referred to us HIA triple therapy is the use of Hydroxychloroquine 200mg per day for three days, Ivermectin 200mcg/kg daily for five days, Azithromycin 500mg per day for three days. None of the patients had been vaccinated.
This was a relatively small sample size but it found that both therapies showed significant reductions in inflammation.
Here’s an excerpt from the study:
The ecacy of ivermectin (IVM) against SARS-CoV-2 has been demonstrated in vitro, while several clinical studies suggest that it is ecacious and safe in reducing morbidity and mortality. Hydroxychloroquine HCQ, IVM and azithromycin AZM (HIA therapy) are being used in several low- and middle-income countries (LMICs) where more expensive medications such as remdesivir are out of reach. In this study, we set out to compare the ecacy of IVM monotherapy with HIA combination therapy.
Methods: This was a single-blind, randomized control trial of 2 parallel groups of COVID-19-positive Nigerians. Thirty patients received ivermectin 200 mcg/kg daily for ve days, while 31 patients received HIA triple therapy. The viral cycle threshold (Ct) at pretreatment baseline and days 2, 5 14 and 21 were measured for the E- and N-genes. SPO2 was assessed on a daily basis, while inammatory markers erythrocyte sedimentation rate (ESR), C-reactive protein, and D-dimer and neutrophil/lymphocyte ratios (NLRs) were assessed at baseline and day 7. Clinical status was self-assessed daily on a Likert scale.
Results: The findings suggest that there were no significant differences in the two groups (ivermectin-only IVM and the HIA triple therapy (IVM+) group) with regard to all the variables. Age and sex were similar, as were dose of ivermectin based on weight, need for supplemental oxygen, and need for ventilator. None of the patients had been vaccinated. Hematological indices such as hemoglobin, white blood count, lymphocyte and neutrophil count, neutrophil/lymphocyte ratio, and platelet count were comparable for both groups. There was also no difference with regard to viral load at baseline for either the N-gene or E-gene. Inflammatory markers such as ESR, C-reactive protein, and D-dimer values were also similar in both groups. SPO[SUB]2[/SUB] was slightly higher for the ivermectin only (IVM) group (93.8% versus 92.0%), but the difference was not statistically significant (P=0.09). Clinical symptoms at baseline, such as diarrhea (23.7%), anosmia (20%), ageusia (18%), dyspnea (25%), headache (50%) and cough (72.1%), were similar in both groups. Therefore, cough was the most common symptom with which patients presented but was slightly less common in the IVM group.
Conclusions: AZT + HCQ may be a redundant adjuvant in COVID-19 therapy. Improvements noted are likely due in large part to ivermectin virucidal and anti-inammatory actions.
Methods: This was a single-blind, randomized control trial of 2 parallel groups of COVID-19-positive Nigerians. Thirty patients received ivermectin 200 mcg/kg daily for ve days, while 31 patients received HIA triple therapy. The viral cycle threshold (Ct) at pretreatment baseline and days 2, 5 14 and 21 were measured for the E- and N-genes. SPO2 was assessed on a daily basis, while inammatory markers erythrocyte sedimentation rate (ESR), C-reactive protein, and D-dimer and neutrophil/lymphocyte ratios (NLRs) were assessed at baseline and day 7. Clinical status was self-assessed daily on a Likert scale.
Results: The findings suggest that there were no significant differences in the two groups (ivermectin-only IVM and the HIA triple therapy (IVM+) group) with regard to all the variables. Age and sex were similar, as were dose of ivermectin based on weight, need for supplemental oxygen, and need for ventilator. None of the patients had been vaccinated. Hematological indices such as hemoglobin, white blood count, lymphocyte and neutrophil count, neutrophil/lymphocyte ratio, and platelet count were comparable for both groups. There was also no difference with regard to viral load at baseline for either the N-gene or E-gene. Inflammatory markers such as ESR, C-reactive protein, and D-dimer values were also similar in both groups. SPO[SUB]2[/SUB] was slightly higher for the ivermectin only (IVM) group (93.8% versus 92.0%), but the difference was not statistically significant (P=0.09). Clinical symptoms at baseline, such as diarrhea (23.7%), anosmia (20%), ageusia (18%), dyspnea (25%), headache (50%) and cough (72.1%), were similar in both groups. Therefore, cough was the most common symptom with which patients presented but was slightly less common in the IVM group.
Conclusions: AZT + HCQ may be a redundant adjuvant in COVID-19 therapy. Improvements noted are likely due in large part to ivermectin virucidal and anti-inammatory actions.
DISCUSSION:
The clinical, virological, inflammatory, and respiratory (SPO[SUB]2[/SUB]%) comparative assessments, which are hard end points of our randomized controlled study, did not show a significant difference between IVM monotherapy and HIA triple therapy in RT-PCR-positive COVID-19 patients. This finding indicates that a combination of AZT + HCQ did not confer any additive benefit to IVM in virucidal action against SARS-Cov-2. The results, however, confirm and extend our earlier results on the anti-SARS-CoV-2 efficacy of ivermectin alone[SUP]4[/SUP].
In this study, we demonstrate further that ivermectin alone or with HIA rapidly increased the cycle time (Ct) of the N-gene (nucleocapsid) and the E-gene (envelope) of SARS-CoV-2 and achieved significant COVID negativity on day 7 on RAMOVA (see Figures 3 and 4).
IVM and HIA were both associated with significantly reduced pro-inflammatory markers CRP, ESR and D-dimer (Figures 6–8), indicative of antithrombotic and cytokine reduction effects of ivermectin via STAT-3 inhibition, as we have previously suggested[SUP]4[/SUP].
Possible side effects of ivermectin: As noted above, there was an overall decrease in the number of complaints by day 5. This suggests that the dose of ivermectin used in this study is safe and efficacious.
In conclusion, there was no significant treatment difference between IVM monotherapy and HIA triple therapy, thus suggesting that AZT + HCQ may be a redundant adjuvant in COVID-19 therapy in Nigerians and elsewhere. There was a highly significant time effect (P< 0.0001 RAMOVA), indicating that the improvements in SARS-CoV-2 N and E-gene Ct, as well as the SPO[SUB]2[/SUB]%, are likely due in large part to ivermectin virucidal and anti-inflammatory actions.
In this study, we demonstrate further that ivermectin alone or with HIA rapidly increased the cycle time (Ct) of the N-gene (nucleocapsid) and the E-gene (envelope) of SARS-CoV-2 and achieved significant COVID negativity on day 7 on RAMOVA (see Figures 3 and 4).
IVM and HIA were both associated with significantly reduced pro-inflammatory markers CRP, ESR and D-dimer (Figures 6–8), indicative of antithrombotic and cytokine reduction effects of ivermectin via STAT-3 inhibition, as we have previously suggested[SUP]4[/SUP].
Possible side effects of ivermectin: As noted above, there was an overall decrease in the number of complaints by day 5. This suggests that the dose of ivermectin used in this study is safe and efficacious.
In conclusion, there was no significant treatment difference between IVM monotherapy and HIA triple therapy, thus suggesting that AZT + HCQ may be a redundant adjuvant in COVID-19 therapy in Nigerians and elsewhere. There was a highly significant time effect (P< 0.0001 RAMOVA), indicating that the improvements in SARS-CoV-2 N and E-gene Ct, as well as the SPO[SUB]2[/SUB]%, are likely due in large part to ivermectin virucidal and anti-inflammatory actions.
Hypothesis:
Null hypothesis (H0): A combination of ivermectin and HCQ+A is not more ecacious in the treatment of patients with virology-proven COVID-19 disease than ivermectin alone.
Alternative Hypothesis (Ha): A combination of ivermectin and HCQ is more ecacious in the treatment of patients with virology-proven COVID-19 disease.
Null hypothesis (H0): A combination of ivermectin and HCQ+A is not more ecacious in the treatment of patients with virology-proven COVID-19 disease than ivermectin alone.
Alternative Hypothesis (Ha): A combination of ivermectin and HCQ is more ecacious in the treatment of patients with virology-proven COVID-19 disease.
Here are some of the questions that were answered by the researchers:
Questions: There was no control group with no treatment, so how do you know that ivermectin was better than no treatment?
Answer: This is a follow-on paper of a previous publication in which we had demonstrated the superiority if ivermectin relative to control. Babalola OE, Bode CO, Ajayi AA, Alakaloko FM, Akase IE, Otrofanowei E, Salu OB, Adeyemo WL, Ademuyiwa AO, Omilabu S. Ivermectin shows clinical benets in mild to moderate COVID19: a randomized controlled double-blind, dose-response study in Lagos, QJM: An International Journal of Medicine, 2021;, hcab035, https://doi.org/10.1093/qjmed/hcab035 Besides, our hypothesis was to test if the addition of HCQ and AZM would increase the therapeutic effect. In the event, it did not appear to do so.
In addition to the aforesaid, regarding our previous double blinded RCT which demonstrated the significant dose-dependent SARS-COV-2 virucidal efficacy of ivermectin, we were ethically constrained, not to deprive any treatment arm and patients, a medication for a potentially fatal disease, which we have shown to be beneficial. No Institutional Review Board would grant approval for such a study on ethical grounds of with holding a therapy. that may be beneficial. just for scientific elegance.
Question:Why is there no control in this work?
Answer: We are not comparing ivermectin with no treatment. We are comparing ivermectin with Ivermectin plus HCQ+IVM (HIA). The work comparing ivermectin with control has already been done and published. It shows a hazard ratio of 2.0 compared to control with regards to viral clearance. (Babalola et al 2021). The hypothesis been tested here is IVM versus HIA.
You can read the full study here: https://www.researchsquare.com/article/rs-950352/v1
New Hampshire Gov. Chris Sununu called for a state lawmaker who’s repeatedly pushed COVID-19 misinformation to be stripped from his leadership position after he blasted out an email to colleagues suggesting that the coronavirus vaccine contains a “living organism with tentacles” and darkens the eyes of newborns.
“I have repeatedly expressed directly to Speaker Packard about the need to remove Representative Weyler from this position of leadership,” the Republican governor said in a statement Monday. “Disseminating this misinformation clearly shows a detachment from reality and lack of judgment.”
“I have repeatedly expressed directly to Speaker Packard about the need to remove Representative Weyler from this position of leadership,” the Republican governor said in a statement Monday. “Disseminating this misinformation clearly shows a detachment from reality and lack of judgment.”
my God! a GOP governor that expects state reps to tell the truth? what a radical proposition. it'll never catch on...
clearly
here is the full video from Oct 29 2019: Universal Flu Vaccine | C-SPAN.org
https://www.youtube.com/watch?v=ViLEzinqzdA&t=60s
Texas restaurant owner fires vaccinated workers
Texas restaurant owner fires vaccinated workers
Absolem
Active member
This post is a prime example why myself and several others here mock people who get their "news" from YouTube.
In less then one minute you will find this claim is bogus. It started as a Tik Tok video and got picked up by the YouTube "news" people and passed off as fact.
You should be ashamed of yourself for the lack of effort you put into your posts. But that's the lazy YouTube "news" way. Spend hours a day listening to YouTube news and not 1 minute spent seeing if what they say is real.
https://www.wmbfnews.com/2021/10/06/...yees-is-false/
LEXINGTON COUNTY, SC (WIS)- A TikTok video showing a South Carolina man saying he fired more than 40 employees for being vaccinated has been viewed more than 80,000 times.
But the owner of the restaurants that man is associated with says no employees at his businesses have been fired because of their vaccination status. In fact, the manager who made that video has been fired.
