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Coronavirus.. outlook

mexcurandero420

mexcurandero420

See the world through a puff of smoke
Veteran
Black licorice was part of some Chinese TCM herbal formulas during the time of SARS in 2003.

SARS prevention for general use:
Isatis root (banlangen) 12 g
Lonicera (jinyinhua) 15 g
Forsythia (lianqiao) 15 g
Coix (yiyiren) 15 g
Pseudostellaria (taizishen) 15 g
Atractylodes (baizhu) 15 g
Licorice (gancao) 9 g



SARS prevention for those of weak constitution with dampness:
Pogostemon (huoxiang) 15 g
Eupatorium (peilan) 9 g
Lonicera (jinyinhua) 12 g
Forsythia (lianqiao) 12 g
Morus leaf (sangye) 15 g
Isatis root (banlangen) 9 g
Atractylodes, fried (baizhu) 15 g
Coix (yiyiren) 18 g
Pseudostellaria (taizishen) 18 g
Licorice (gancao) 9 g
 
Phaeton

Phaeton

Speed of Dark
Veteran
Medfinder said:
Diabetes Drug Metformin May Reduce COVID-19 Death Risk

Source: MedicineNet Health News

Can a common, first-line diabetes drug protect COVID-19 patients from death? Studies suggest a link, but trials necessary to prove a connection may never happen, experts say.

People with type 2 diabetes stand a higher risk of developing a severe COVID 19 infection, according to several international studies. Metformin has been correlated in at least four retrospective studies with reduced risk of COVID-19 death in these patients.

https://www.medicinenet.com/diabetes_drug_metformin_may_reduce_covid_19_death-news.htm
Click to expand...

Wow, two more coincidence medications. This is twice now for me. I am on daily Plavix to prevent blood clots and I have a stash of Metformin from when my type 2 Diabetes was a problem.

I have heard rumors of THC damping down lung constriction but suspect ingesting it with carcinogenic smoke may neutralize the positives. Vaping is my compromise.

My son in law is type 1 Diabetes so if either of us catch covid-19 my daughter will be on her own.
An extra worry and a powerful incentive for preventive measures.
 
Switcher56

Switcher56

Comfortably numb!
Medfinder said:
Diabetes Drug Metformin May Reduce COVID-19 Death Risk

Source: MedicineNet Health News

Can a common, first-line diabetes drug protect COVID-19 patients from death? Studies suggest a link, but trials necessary to prove a connection may never happen, experts say.

People with type 2 diabetes stand a higher risk of developing a severe COVID 19 infection, according to several international studies. Metformin has been correlated in at least four retrospective studies with reduced risk of COVID-19 death in these patients.

https://www.medicinenet.com/diabetes_drug_metformin_may_reduce_covid_19_death-news.htm
Click to expand...
Interesting :) I'm on 2000mg/day not that I'm about to stake my life on it however.

That being said, it is hard on the kidneys and liver, not to mention the heart as it stops the production of the CO-enzime CQ10, which the heart needs for normal function. I supplement it.
 
Medfinder

Medfinder

Chemon 91
Coronavirus Cases:
32,475,057
view by country
Deaths:
988,735
Recovered:
23,969,496
ACTIVE CASES
7,516,826
Currently Infected Patients
7,453,398 (99%)
in Mild Condition

63,428 (1%)

Show Statistics
CLOSED CASES
24,958,231
Cases which had an outcome:
23,969,496 (96%)
Recovered / Discharged

988,735 (4%)
Deaths:comfort:
 
armedoldhippy

armedoldhippy

Well-known member
Veteran
i took metformin for weeks, had to drop it. damn stuff made my legs hurt so bad that i could not sleep. have talked to others that it affected the same way. nothing works for everyone...
 
mexcurandero420

mexcurandero420

See the world through a puff of smoke
Veteran
Switcher56 said:
where you supplementing magnesium at the time?
Click to expand...

And don't forget vitamin B12

The proposed mechanisms to explain metformin induced vitamin B12 deficiency among patients with T2DM include: alterations in small bowel motility which stimulates bacterial overgrowth and consequential vitamin B12 deficiency, competitive inhibition or inactivation of vitamin B12 absorption
Click to expand...
 
mexcurandero420

mexcurandero420

See the world through a puff of smoke
Veteran
HEALTHY AND YET CRITICALLY ILL FROM CORONA? SCIENTISTS REVEAL HOW THAT CAN HAPPEN

In about 14 percent of cases, it can be traced back to problems with the own immune system.

Everyone knows that the coronavirus is especially dangerous for elderly people and people who already have certain health problems. But every now and then we see that relatively young and previously completely healthy people end up in intensive care and even die due to the virus. What's going wrong in their bodies? Scientists have figured it out and come up in two studies with two causes that together can explain about 14 percent of the cases in which otherwise healthy people become deathly ill due to SARS-CoV-2.

Two studies
In the first study, the scientists show that just over ten percent of healthy people who become seriously ill from the virus produce antibodies that attack their own immune system, not the virus. And at least 3.5 percent of healthy people who become seriously ill with the virus have genetic mutations that hinder an effective response of the immune system to the virus. This can be read in the magazine Science .

Type I Interferons play a key role in both studies. Interferons are proteins that are part of the so-called intrinsic and innate immune system. They come into action - even before the adaptive immune system in response to the presence of virus particles, for example, starts to produce antibodies - and play an important role in strengthening cell defense. The term type I interferons refers to a set of 17 proteins that in this way are of great importance during a viral attack for the protection of cells and thus the body. "Type I Interferons are small proteins that can be produced at a rapid rate by many different cell types after infection by a pathogen - such as a virus," says researcher Stuart Tangye. And these proteins are also of great importance in the fight against SARS-CoV-2, according to experiments in which researchers released the virus on cells that did not produce these proteins or did not produce them sufficiently. Compared to cells that did have the proteins ready, these cells died much more often - and remarkably quickly. These interferons are therefore very important. And the two new studies now show that a flaw around these type 1 Interferons underlies life-threatening forms of COVID-19.

Study I
For example, the first study - conducted among 987 critically ill COVID-19 patients - showed that 10.2 percent of the patients had neutralizing auto-antibodies that did not deal with the virus, but with the type I interferons. During their illness, this led to a low or even undetectable concentration of these proteins. “And what's interesting is that 94 percent of the patients with these neutralizing autoantibodies were male. It may help explain why men are more prone to a severe form of COVID-19. ”

The good news is that autoantibodies don't seem to be very common. This is evident from a study among 1227 completely randomly selected healthy people. Only four of them had the auto-antibodies. Research also shows that these autoantibodies could already be detected in some people before the virus infection. And in others, early in the infection, before the immune system had time to take action. “All of this strongly suggests that these autoantibodies are the underlying reason some people become seriously ill and are not a consequence of the infection,” emphasizes researcher Jean-Laurent Casanova.

Study II
In the second study , scientists looked at 659 seriously ill corona patients. "They studied the genes that encode 13 proteins that are very important when it comes to protecting against viral infections," says Professor John Christodoulou, not involved in the study, but with one of the consortiums that participated in the study. "And they found that 3.5 percent of patients with severe COVID-19 had some changes in these genes." And those gene mutations - not found in a control group of 534 corona patients with no symptoms or mild symptoms - prevent the immune system from producing or responding to type I interferons.

Mysterious
“The different ways SARS-CoV-2 affects people are puzzling,” says Christodoulou. "The virus can cause a symptom-free infection and disappear quietly or kill people in a matter of days." Scientists would of course like to know why the course of the disease is so different and these studies help with that. "Together they show that faults in the protective interferon system are at the root of as many as 14 percent of critically ill COVID-19 cases," says Professor Paul Hertzog.

More research is of course badly needed. "It is likely that follow-up studies will reveal further defects that prevent the body from initiating an effective antiviral response," said Hertzog. Such studies are important for several reasons; they can thus lead to a better understanding of the disease and the discovery of an effective treatment. “The results provide us with compelling evidence that type I interferon disruption is often the cause of life-threatening forms of COVID-19,” Casanova said. "And these problems can - at least in theory - possibly be treated with existing medications and interventions."

scientias.nl
 
N

Nannymouse

Well-known member
✅
Teacher's perspective:look out.

Each of the winter's holidays is going to kick up the cases. In the USA, the biggy events will be halloween, thanksgiving, christmas, new years. Teachers see this every year with colds, flu, head lice. I doubt that this virus will take time off. Seasonal colds and flu will complicate some of the covid cases.

Take care, out there.
 
Medfinder

Medfinder

Chemon 91
Coronavirus Cases:
32,801,471
view by country
Deaths:
994,260
Recovered:
24,198,074
ACTIVE CASES
7,609,137
Currently Infected Patients
7,545,206 (99%)
in Mild Condition

63,931 (1%)
Serious or Critical
Show Statistics
CLOSED CASES
25,192,334
Cases which had an outcome:
24,198,074 (96%)
Recovered / Discharged

994,260 (4%)
Deaths:comfort:
 
Im'One

Im'One

Active member
Nannymouse said:
Teacher's perspective:look out.

Each of the winter's holidays is going to kick up the cases. In the USA, the biggy events will be halloween, thanksgiving, christmas, new years. Teachers see this every year with colds, flu, head lice. I doubt that this virus will take time off. Seasonal colds and flu will complicate some of the covid cases.

Take care, out there.
Click to expand...

I applied for a virtual teaching gig at our district. I hate virtual teaching only slightly less than I hate dying
 
Medfinder

Medfinder

Chemon 91
Coronavirus Cases:
33,118,009
view by country
Deaths:
999,574
Recovered:
24,459,750
ACTIVE CASES
7,658,685
Currently Infected Patients
7,593,297 (99%)
in Mild Condition

CLOSED CASES
25,459,324
Cases which had an outcome:
24,459,750 (96%)
Recovered / Discharged

999,574 (4%)
Deaths:comfort:
 
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