Ich habe endlich eine Studie gefunden zum Thema Größe von Liposomen und schneller Aufnahme ins Blut.
Nanopartikel scheinen keine Voraussetzung zu sein um eine schnelle Aufnahme zu gewährleisten
"The liposomes vary in size between 400 and 3000 nm."
...
"After only 10 to 15 minutes, an uptake trough the wall of the jejunum could be detected"
Das Rezept ist auch drin:
2.1. Liposomal Packaging A total of 477 g of distilled water, 115 g of Ethanol (98% vol., Weisshaus GmbH, Füssen, Germany), 161 g of ascorbic acid (Golden Peanut GmbH, Garstedt, Germany), and 13 g of MgCl2 is mixed in a glass flask and constantly stirred while placed in an ultra-sonic water bath, until all parts of the solution are completely dissolved. Subsequently, 197 g of lecithin (Powder, from Sunflower, IVOVITAL, Hofgeismar, Germany) is added and mixed with a blender using average speed. The mixture is incubated at 4 ◦C for 24 h and stirred every 6 hours for 4 minutes. Afterwards, the mixture is poured in a glass flask and placed in an ultra-sonic bath for 45 minutes in order to degas the mixture, in which causes foam on the surface area. The foam is discarded and the remaining mixture is placed in an ultra-sonic water bath again for another 45 minutes. During the two ultra-sonic bath treatments, the water temperature might increase, and in that, case should be replaced by cold water since liposomes tend to resolve when exposed to a higher temperature than 37 ◦C. The mixture is divided into 50 ml portions for oral intake, of which each one consist of 11.0 g of lecithin, 6.4 g of ethanol (98%), 33.5 g of purified water, and 9 g of vitamin C. Noteworthy, all ingredients can be purchased in online shops or in local drug stores
Nanopartikel scheinen keine Voraussetzung zu sein um eine schnelle Aufnahme zu gewährleisten
"The liposomes vary in size between 400 and 3000 nm."
...
"After only 10 to 15 minutes, an uptake trough the wall of the jejunum could be detected"
Das Rezept ist auch drin:
2.1. Liposomal Packaging A total of 477 g of distilled water, 115 g of Ethanol (98% vol., Weisshaus GmbH, Füssen, Germany), 161 g of ascorbic acid (Golden Peanut GmbH, Garstedt, Germany), and 13 g of MgCl2 is mixed in a glass flask and constantly stirred while placed in an ultra-sonic water bath, until all parts of the solution are completely dissolved. Subsequently, 197 g of lecithin (Powder, from Sunflower, IVOVITAL, Hofgeismar, Germany) is added and mixed with a blender using average speed. The mixture is incubated at 4 ◦C for 24 h and stirred every 6 hours for 4 minutes. Afterwards, the mixture is poured in a glass flask and placed in an ultra-sonic bath for 45 minutes in order to degas the mixture, in which causes foam on the surface area. The foam is discarded and the remaining mixture is placed in an ultra-sonic water bath again for another 45 minutes. During the two ultra-sonic bath treatments, the water temperature might increase, and in that, case should be replaced by cold water since liposomes tend to resolve when exposed to a higher temperature than 37 ◦C. The mixture is divided into 50 ml portions for oral intake, of which each one consist of 11.0 g of lecithin, 6.4 g of ethanol (98%), 33.5 g of purified water, and 9 g of vitamin C. Noteworthy, all ingredients can be purchased in online shops or in local drug stores
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