I’ve had mine for more than 40 years and really don’t think it’s going away like an aftermarket birthmark. I do have to file it down now and then when it gets rough enough to grab onto clothing. I have other scars and dings also from my life's ups and downs.Dont know about womens hands being more common.
Maybe now considering most young guys are kinda weak with most of their callouses from playing with Pokemon.
I still have a big one on my right thumb from twisting wirenuts for 55 years.