it seems you have got a good eye for the male female thing. if i wanted to make seeds, i would wait to remove the males till they have made the top into colas of male flowers, when you notice the flowers are fully formed but not open yet, you can remove it and it should open the flowers what ever you do, lol. in my experience male flowers grow and open even in 18/6 once they get mature (big). but so far i assume there are only a few pre-flowers visible, right? so there is no rush to get them out, just keep an eye on them.