I have been smoking since 1968, hash in Germany got me started. My oldest bro he's 70, is currently under going treatment for AML leukemia, cause by radiation treatments for colon cancer. we have been keeping him high with the use of tinctures brought in to the hosp. with out them knowing. Anyway he has been a serious smoker for the last 25 years his cancer doc said theres nothing wrong with his organs lungs brain etc( we're getting ready to do a T cell transplant if all works out. So, back to the subject, both of us have been smoking for over 40 years daily and a lot. Neither of us suffers from any ill effects unless we run out then its jones time and that just don't happen.