Citric acid convert some of the ingredients
If the extract is heated or kept for too long, the psilocybin is converted to psilocin. The alkaloids are quite soluble in acid and it doesn't take long to extract them at room temperature. Methanol gives a cleaner extract that can be evaporated and then defatted and all, without alteration.
Nasal spray sounds fun
I hereby claim an invention comprising mushroom alkaloids in a suppository formulation. HappyButt *TM Pre-order now or be left out.
Psilocybin pills in a pharmacy just like any other drug sounds funner.