illuminatus
Member
I don't know about you, but I've never smoked mj that was to potent. I can't wait till I find some, when I do I'll let you all know about it.
tuco88 said:The smells got me. Man, I love the way good pot smells.
To be honest, I don't smoke it very often anymore, haven't had any in probably 18 months. Don't eat it, don't vaporize it, just smell it and look at it. Just grow it for the smell and beauty.
Seriously.
When I get a good plant going, just walking into the room and taking a big whiff, I can feel that warm pressure in my forehead behind my eyes building, my skin gets tingly, all that. I get about 50% high just being in the room with them, looking at the leaves and inhaling the aromas. The aromatic terpenes are mostly satisfying enough, mmmmmmm.
I'm not addicted to the high, I'm addicted to being around the plant.
How ****ing weird is that?
I love that plant... Why the hell does it have to be illegal. Gahhh.
Humans don't have cell walls, but we do have cell membranesTruthman said:An example is fats, most don't know that eating different types of fats will help with your cells uptake of cannabinoids and terpenoids and how long they will stay on the cell wall because they each do something different.
If you meant cell membranes I've never heard of this. My understanding was that cell membranes are quite stable in their composition and not significantly affected by diet. There is a very delicate physiologic balance and if diet changed fat permeability to any significant extent it would have disastrous effects on the body's other essential functions.Truthman said:For example, short and medium chain fats get the cell walls to become more flexible and to allow the heavier oils to attach easier BUT they don't last that long, this is when the saturated fats help because they keep the fats in place longer BUT if there is too much saturated fat, the cell walls will become stiif and this is where the monounstaurated fats help because they keep the cell membrane flexible but for a longer time than the short and medium chain fats but they too have a little saturated fat in them and this is where the polyunsaturated fat comes in and keeps the cell flexible for a longer time because they stay liquid constantly.
Psychoactive affects come from binding of cannabinoids to cannabinoid receptors on neuronal tissue. Flexibility of the membrane plays no role. The receptors are on the surface of the membrane and do not need to pass through it.Truthman said:These fat keep the cannabinoids and terpenoids in the cell membranes for a longer time than someone who doesn't eat right and have a flexible cell membrane and would therefore NEED a potent herb just to feel the regular effects they used to because their cell membrane is too stiff.
What hormones are these?Truthman said:It also means that they won't have enough of the hormones in a balanced ratio, that cannabis releases and gives the highs that each strain is known for.
I agree that diet can have subjective affects but they won't be necessarily better or worse. E.g. a poor diet can reduce the body's metabolism rate for THC and prolong its activity.Truthman said:This is why a diet high in good fats, complex carbs, and protein is needed to feel the optimum effects of cannabis without needing a potent strain to do this. Of course potency makes it even better but it isn't needed.
THC and other active cannabinoids degrade principly by hydroxylation, not oxidation.Truthman said:Antioxidants & vitamins is another thing that is needed because they keep the oils from oxidizing which will keep the cannabinoids from degrading which means a longer high as well as help make more hormones and start certain processes in the body going.
Those symptoms are psychological and heavily dependent on the mindset of the individual. Although eating a better diet has been shown to help anxiety which would put the using in a better mindset.Truthman said:You also don't have the paranoia, sweating, and anxiety that comes along with smoking potent hash because your body is well equipped to deal with the potency of the herb and the quick changes in the body that comes along with ingesting/inhaling potent herbs.
I agreed with your main point, having a healthy body enhances my high but for different reasons then you mention. I.e. if we feel great already from being healthy that will just add to the joy of the high.Truthman said:So, in order to truly be able to judge what each strain really does, you have to have your body in optimum strength so your nerves can handle these potent herbs, this is where exercise comes in, and you need a huge amount of chemicals stored so your body can release what's needed when certain chemicals bind to certain receptors.
house said:Humans don't have cell walls, but we do have cell membranes
If you meant cell membranes I've never heard of this. My understanding was that cell membranes are quite stable in their composition and not significantly affected by diet. There is a very delicate physiologic balance and if diet changed fat permeability to any significant extent it would have disastrous effects on the body's other essential functions.
Psychoactive affects come from binding of cannabinoids to cannabinoid receptors on neuronal tissue. Flexibility of the membrane plays no role. The receptors are on the surface of the membrane and do not need to pass through it.
What hormones are these?
I agree that diet can have subjective affects but they won't be necessarily better or worse. E.g. a poor diet can reduce the body's metabolism rate for THC and prolong its activity.
THC and other active cannabinoids degrade principly by hydroxylation, not oxidation.
Those symptoms are psychological and heavily dependent on the mindset of the individual. Although eating a better diet has been shown to help anxiety which would put the using in a better mindset.
I agreed with your main point, having a healthy body enhances my high but for different reasons then you mention. I.e. if we feel great already from being healthy that will just add to the joy of the high.
I stand corrected, thanks for the linkTruthman said:
This link says linoleic acid, an unsaturated fatty acid reduced serotonin, prolactin and formyl-Met-Leu-Phe binding. How does reduced affinity from membrane fluidization make them stay in them membrane longer and give a better high? Wouldn't the opposite occur?Truthman said:
Sure it will, THC doesn't stay in fat cells indefinitely, it eventually exits back into the bloodstream as an active compound where it can bind to cb receptorsTruthman said:Having a slow metabolism WON'T prolong thc's activity just simply because it won't get used up. The body will quickly put it into fat cells. This is why people get fat who are seditary which is because they consume more than they use up.
I agree oxidation occurs but oxidation from free radicals is not the principle means of degradation. THC is mainly metabolized by enzyme hydroxylation, this is apparent from looking at the metabolites.Truthman said:Cannabis does degrade by oxidation due to the free radicals. Look at it like this if cannabis is attached to fat that suck up oxygen, which is what fat does, eventually the oxygen will beat it down and degrade it. This is one reason why thc is shown to be a potent antioxidant which I feel is because it is made to protect the plant when it is grown in an oxygen rich environment which is outside.
From your own citation THC reduces these adrenal hormones:"delta 9-THC treatment resulted in a significant decrease in plasma and MBH levels of norepinephrine (NE), epinephrine (E)"Truthman said:Paranoia & anxiety are symptoms that are very real and is due to the thc being a stimulant releasing adrenal hormones and this gets the body going.
THC has both stimulate and depressive effects and I wouldn't classify it as a pure stimulant. Vitamin C sounds interesting so I'll give it a try, any advice when and how much to take? I said the paranoia, anxiety and sweating are dependent on mindset because I know several smokers who overcame this by just learning to relax and letting go. It may be a lack of Vit C but sometimes people are just too stressed and not in the right mindset and this leads to bad expiriences. Truthman, I don't mean to come across as hostle or put anyone down. I like debates and have found your posts to be very informative. You are my cannabis brother and it's all in good fun here.Truthman said:If you don't have enough yet still ingest high amounts of thc, you will get these symptoms. This is why I feel vitamin C is one of the main things that can prevent this. I KNOW for a fact this one little thing when taken in the right amount and at the right time prevents these problems. I've done as well as others. This why people who take small puffs don't get symptoms yet if they keep going the problems start and its due to the lack of the body being able to handle the excess stimulation being inside it from the thc, which is a stimulant.