Treating Cancer with Concentrates Thread

[LostTribe]

yes the oils will extract cannabinoids from the bud

But most would use an already extracted cannabis concentrate to add to the coconut oil.

 

[Gray Wolf]

[FONT=Arial, Helvetica, sans-serif]"the oil should have extracted a great amount of compounds no? "[/FONT]

It should have extracted quite a bit, but you'd guess at a dose and the concentration would be low. I was thinking just a BHO done, off dry but fresh material, with no warm water/boil off and no heat purge (no vacuum here) and just let sit for long enough dust free, cool and out of light, to turn to shatter?

If you'd combine that with an oil, olive or coconut or whatever, you could get the concentration you desire to dose easily. 50/50 or whatever..

Thanks GW for your input, no access to meds like that here for me (actually now that I think I might have an avenue!), but thanks I'll note that for recommending to patients.

Citicolene is readily available on line via Google. IE:

https://www.vitaminshoppe.com/p/jar...ps&source=go&gclid=CLLAgKb-vtACFU9bfgodszgFLw

Also to get real CBD oil here is a mission and cuts of real CBD genetics also mission, I'd have to ship em illegally in myself, they couldn't actually prosecute but that's another story..The locally available CBD oil is generally expensive and I doubt its authenticity. The THC oil I can vouch for as I can make it.. No way to get lab tests done here except by sending to a foreign lab. But also was thinking about more about this recently activated/non activated..G.W. maybe you can help me understand?

Now the activated, why is it activated, ie. decarbed.

So that it more readily passes the blood brain barrier, to reach the CB-1 receptors in the brain. The molecule is too big to readily pass with the COOH carboxyl chain attached to the THC molecule.

It isn't water soluble unlike the acid salt of an alkaloid, but when I smoke the stuff, it gets into my blood pretty efficiently and hits receptors around my nervous system, or does it hit my brain mainly..anyways, inspite of it not being so water soluble it gets around in an instant and I can feel the evidence of this..Is this because it is more polar being decarbed now and hence "activated" being able to zoom around my bloodstream more efficiently and get me high now?

No, it is just small enough to pass the blood brain barrier to reach the CB-1 receptors in the brain, that make you high.

Or have I understood it wrong, that is just my layman understanding.. does the carboxyl group make it not fit the receptor that makes me high, would it then still trigger another cannabanoid receptor to assist in cancer..does it need to trigger the ones to get me high to assist in cancer? Hmmm

Because I have two issues with that first understanding, one hash eating, which has a long history in culture. That has been decarbed, does the pressing of the block before it reaches market, or something else like aging from time in transit or heat in storage etc. effectively decarb that so it is active to be eaten. As people reliably ate it and they got pretty bloody high, even tripped out haha but it has never in my thinking been "decarbed". Is it because if the large doses involved and/or lack of tolerance or is the stuff active anyways..Which leads me to my second issue, is that if the un"activated" or non-decarbed oil is less psycho-active, is that because of it being less polar and therefore harder to absorb into the gut and blood and get to the cannabanoid receptors...and therefore in my mind going to be as proportionately physiologically active also, for anti cancer etc.. as less stuff is able to get around the body to where it would help being less blood soluble. Is my reasoning here that less psycho-activity equates to less medical benefit correct or off the mark? If so either way I am barking up the wrong tree with non-activated oil and the patients must deal with getting high then..anyways thinking aloud, please GW if you could chime in again if around..

Check above. One size doesn't fit all.........

 

[TnTLabs]

GW i remember you from when i first joined many years ago.. i was always able to pick up some useful infos from your posts... you know your stuff!
thanks for your input

 

[maryjaneismyfre]

Thanks so much GW!

So the non-decarbed oil will still be as medicinally active, just not at all as psycho-active (or pain numbing but that not what I'm looking for) basically..? Excellent!

Reading up on the citocoline, seems like something I want to get for myself too! Good stuff thanks man

 

[superglue]

regarding hash being decarbed...
i read somewhere years ago that in days of yore(hashassins),
hash was customarily aged at least a year before it was consumed to cure it so that it did not make you crazy when consumed and that tidbit would explain why it was psychologically active


lt,
There are hundreds of paths up the mountain,
all leading in the same direction,
so it doesn’t matter which path you take.
The only one wasting time is the one
who runs around and around the mountain,
telling everyone that his or her path is wrong.

 

[TnTLabs]

that would make sense as i know a lot of hash smokers that cant deal with weed as it fucks them up mentally.... so i guess more thc is converted into cbd & co with hash like mentioned before

 

[superglue]

not to nit pick but...
thc-a loses it's cooh group with age or heat and becomes d9thc which with time or heat becomes d8thc and that becomes cbn

cbd however won't come from thc unless you use some form of isomeration on it

cbg-a is the root from which thc-a and cbd-a originate but they are separate pathways because the enzymes that transformed them are different

edit to add: btw..d9thc transforms into d11thc in the liver of most people when they eat it(some folks don't process it)

 

[LostTribe]

straight buds can also be decarboxylated with simple aging although I cannot remember the precise amount of time he waits but think it was over 90 day cure.... A member on the ACE forum only eats his buds as he has some medicinal issues and never smokes or vapes. He ages or warms the buds in the oven i think he's tangwena or something like that....he just eats the buds whole sometimes and kicks back and enjoys the ride.

 

[TnTLabs]

not to nit pick but...
thc-a loses it's cooh group with age or heat and becomes d9thc which with time or heat becomes d8thc and that becomes cbn

cbd however won't come from thc unless you use some form of isomeration on it

cbg-a is the root from which thc-a and cbd-a originate but they are separate pathways because the enzymes that transformed them are different

edit to add: btw..d9thc transforms into d11thc in the liver of most people when they eat it(some folks don't process it)

no harm done! many thanks for the clarification!

 

[TnTLabs]

Aloe arborescens is also great plant for treating cancers as she works as anti-mutagen..

https://en.wikipedia.org/wiki/Aloe_arborescens

Thing is you need to use plant that is atleast 5 years old,its easy recipe
where you mix 500 grams of good organic honey,350 grams of leafes that are cleaned
from stings and 100 ml of quality desitilate alchohol (wiskey,votka,rakija) of 40% strong,
very important thing is to made cure in total dark and later put it in jar that
is totally black cause main medical active ingredient is very photosensitive,
taking cure every day in dark room whithouth light 3 times(morning,midday,evening) till you finish jar.

Children from Chernobil was treated with this plant in one Itallian clinic,
Father Romano Zago was write book on healing with this plant,

if you are interested you can google more on her..

i think all over the world mother nature has different resources one can make use of to heal all illnesses..
knowledge is the only thing we are lacking... its all there in front of us..
i hear the same potential about dandelion roots.. a plant that can be found nearly everywhere on the planet

 

[Dog Star]

Dandelions are mighty flowers... its cold here,about -5 thru a hole day and still
i sees some dandelion flowers here close in garden opened yellow and alive.

Dandelions are also important part of Biodynamic agriculture as there they made
teas or use dryed dandelions as a compost stabilizer,Steiner was brilliant mind.

 

[LostTribe]

regarding hash being decarbed...
i read somewhere years ago that in days of yore(hashassins),
hash was customarily aged at least a year before it was consumed to cure it so that it did not make you crazy when consumed and that tidbit would explain why it was psychologically active

lt,
There are hundreds of paths up the mountain,
all leading in the same direction,
so it doesn’t matter which path you take.
The only one wasting time is the one
who runs around and around the mountain,
telling everyone that his or her path is wrong.

That makes zero sense as allowing it to age decarb's it naturally causing it to become psychoactive.

 

[trichrider]

Cancer- glioma/ brain

Anti-tumor effects of cannabidiol
http://www.hempworld.com/HempPharm/...milanstudy.html

Pot’s cancer healing properties
http://www.november.org/stayinfo/br...ncerKiller.html

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
http://cancerres.aacrjournals.org/c...hort/64/16/5617

Inhibition of Glioma Growth in Vivo
http://cancerres.aacrjournals.org/c.../61/15/5784.pdf

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
http://www.cannabis-med.org/studies...ow.php?s_id=193

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
http://www.ihop-net.org/UniPub/iHOP...l?pmid=16909207

Cannabinoid receptors in human astroglial tumors
http://www.brainlife.org/abstracts/...t_j20060800.pdf

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
http://www.medicalnewstoday.com/articles/12088.php

THC tested against brain tumor in pilot clinical study
http://www.cannabis-med.org/english...el.php?id=222#1

Cures Brain Cancer

http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html
http://www.ncbi.nlm.nih.gov/pubmed/11479216
http://www.jneurosci.org/content/21/17/6475.abstract
http://jpet.aspetjournals.org/content/308/3/838.abstract
http://mct.aacrjournals.org/content/10/1/90.abstract
http://www.ncbi.nlm.nih.gov/pubmed/17952650
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576089/
http://www.jci.org/articles/view/37948
http://cancerres.aacrjournals.org/content/64/16/5617.full

there are more links related to other cancers in the thread below...

https://www.icmag.com/ic/showthread.php?t=278827

LostTribe...you gave me a bump to add the links above and i don't remember doing so...forgive me if i have already hooked you up, and if not, surprise!

 

[TnTLabs]

great post! thx trichrider

 

[LostTribe]

Cancer- glioma/ brain

Anti-tumor effects of cannabidiol
http://www.hempworld.com/HempPharm/...milanstudy.html

Pot’s cancer healing properties
http://www.november.org/stayinfo/br...ncerKiller.html

Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas
http://cancerres.aacrjournals.org/c...hort/64/16/5617

Inhibition of Glioma Growth in Vivo
http://cancerres.aacrjournals.org/c.../61/15/5784.pdf

Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.
http://www.cannabis-med.org/studies...ow.php?s_id=193

Cannabidiol triggers caspase activation and oxidative stress in human glioma cells.
http://www.ihop-net.org/UniPub/iHOP...l?pmid=16909207

Cannabinoid receptors in human astroglial tumors
http://www.brainlife.org/abstracts/...t_j20060800.pdf

Cannabis extract makes brain tumors shrink, halts growth of blood vessels
http://www.medicalnewstoday.com/articles/12088.php

THC tested against brain tumor in pilot clinical study
http://www.cannabis-med.org/english...el.php?id=222#1

Cures Brain Cancer

http://www.nature.com/bjc/journal/v95/n2/abs/6603236a.html
http://www.ncbi.nlm.nih.gov/pubmed/11479216
http://www.jneurosci.org/content/21/17/6475.abstract
http://jpet.aspetjournals.org/content/308/3/838.abstract
http://mct.aacrjournals.org/content/10/1/90.abstract
http://www.ncbi.nlm.nih.gov/pubmed/17952650
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576089/
http://www.jci.org/articles/view/37948
http://cancerres.aacrjournals.org/content/64/16/5617.full

there are more links related to other cancers in the thread below...

https://www.icmag.com/ic/showthread.php?t=278827

LostTribe...you gave me a bump to add the links above and i don't remember doing so...forgive me if i have already hooked you up, and if not, surprise!

Its all to the good brother thanks for posting! Great info in there!

 

[angelgoob]

Just an anecdotal info, in my case Ginseng and caffeine mitigate the effects of THC slightly.

I've also tried citicoline and that works also, along with caffeine.

 

[LostTribe]

Just an anecdotal info, in my case Ginseng and caffeine mitigate the effects of THC slightly.

I've also tried citicoline and that works also, along with caffeine.

Thats good to know. Caffeine has always been recommended even going back to when folks visiting Amsterdam would get wasted on tabaco mixed spliffs.

 

[TnTLabs]

Thats good to know. Caffeine has always been recommended even going back to when folks visiting Amsterdam would get wasted on tabaco mixed spliffs.

eating citrus fruits / vitamin c helps to break down THC faster if i remember correct..

 

[Sluicebox]

Great thread

 

[LostTribe]

If you guys didnt see the Hash Church with Dr. Melamede the link is a few pages back a few links down you can find the time he is on. Great show.