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Study finds abnormally low blood flow in the brain of marijuana users

dddaver

Active member
Veteran
My first impression is: yeah? so? How is this necessarily a bad thing? It seems like just a high tech scare tactic. Didn't work on me.

Study finds abnormally low blood flow in the brain of marijuana users

Hippocampus, the brain's key memory and learning center, has the lowest blood flow in marijuana users suggesting higher vulnerability to Alzheimer's. As the U.S. races to legalize marijuana for medicinal and recreational use, a new, large scale brain imaging study gives reason for caution.
Published in the Journal of Alzheimer's Disease, researchers using single photon emission computed tomography (SPECT), a sophisticated imaging study that evaluates blood flow and activity patterns, demonstrated abnormally low blood flow in virtually every area of the brain studies in nearly 1,000 marijuana compared to healthy controls, including areas known to be affected by Alzheimer's pathology such as the hippocampus.
All datawere obtained for analysis from a large multisite database, involving 26,268 patients who came for evaluation of complex, treatment resistant issues to one of nine outpatient neuropsychiatric clinics across the United States (Newport Beach, Costa Mesa, Fairfield, and Brisbane, CA, Tacoma and Bellevue, WA, Reston, VA, Atlanta, GA and New York, NY) between 1995-2015. Of these, 982 current or former marijuana users had brain SPECT at rest and during a mental concentration task compared to almost 100 healhty controls.
Predictive analytics with discriminant analysis was done to determine if brain SPECT regions can distinguish marijuana user brains from controls brain. Low blood flow in the hippocampus in marijuana users reliably distinguished marijuana users from controls.
The right hippocampus during a concentration task was the single most predictive region in distinguishing marijuana users from their normal counterparts. Marijuana use is thought to interfere with memory formation by inhibiting activity in this part of the brain.

According to one of the co-authors on the study Elisabeth Jorandby, M.D., "As a physician who routinely sees marijuana users, what struck me was not only the global reduction in blood flow in the marijuana users brains, but that the hippocampus was the most affected region due to its role in memory and Alzheimer's disease.
Our research has proven that marijuana users have lower cerebral blood flow than non-users. Second, the most predictive region separating these two groups is low blood flow in the hippocampus on concentration brain SPECT imaging.
This work suggests that marijuana use has damaging influences in the brain - particularly regions important in memory and learning and known to be affected by Alzheimer's."
Dr. George Perry, Editor in Chief of the Journal of Alzheimer's Disease said, "Open use of marijuana, through legalization, will reveal the wide range of marijuana's benefits and threats to human health. This study indicates troubling effects on the hippocampus that may be the harbingers of brain damage."
According to Daniel Amen, M.D., Founder of Amen Clinics, "Our research demonstrates that marijuana can have significant negative effects on brain function. The media has given the general impression that marijuana is a safe recreational drug, this research directly challenges that notion. In another new study just released, researchers showed that marijuana use tripled the risk of psychosis. Caution is clearly in order."


http://www.news-medical.net/news/20...ood-flow-in-the-brain-of-marijuana-users.aspx
 
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We know that cannabis lowers blood pressure. I'm guessing that's what they're getting at in a negative light. Compare the findings with other vasodilators and see what you get...probably the same thing
 

Beanzy

Active member
Lol... I am laughing at the analogies . Any study can find whatever they want to find, but I still like the taste of pizza when blood flow is low in the membrane.
In all seriousness though.... the use of nicotine constricts the blood vessels inhibiting blood flow to the brain yet a pack of cigs doesn't put you behind bars. I am most certain that the worse physical side effect of cannabis far outweighs the benefits even if the benefit is a better mood and a brighter outlook.
 

bombadil.360

Andinismo Hierbatero
Veteran
Wouldn't it be easier to just evaluate people already diagnosed with Alzheimer’s disease to see how many were cannabis users to determine any relation?
 

Tonygreen

Well-known member
ICMag Donor
Veteran
They are from some weird psychiatric clinic in Socal.
I'm pretty sure the majority of people they treat smoke weed.
They could link it to anything if they wanted to.
A slick "study" to advertise and grow their business.
 

Beanzy

Active member
They are from some weird psychiatric clinic in Socal.
I'm pretty sure the majority of people they treat smoke weed.
They could link it to anything if they wanted to.
A slick "study" to advertise and grow their business.
You hit it on the head, sheldon Adelson a casino tycoon spends millions s a year fighting MMJ, he also owns a string of rehab centers. There is a group of mental health workers fighting it and they are all connected and I suspect share common donators to their twisted studies.
 

nukklehead

Active member
Dont know about the hippocampus being affected by usage but Alzheimers is due to amyloid plaque buildup in all areas of the brain. Therefore there is no relationship to Alzheimers disease. As a user, I feel I do have some short term memory loss. Is it due to cannabis? I dont know. Or I cant remember..:).... But for sure Alzheimers is not related to usage. If you get a chance see 60 minutes TV show last Sunday. Seems to prove a definite genetic / DNA mutation that is the biggest cause of Alzheimers.
 

Dog Star

Active member
Veteran
But is this study talks on smoking Cannabis or ingesting BHO,cookies,etc other edibles??


We all know that smoking is not good for body,specialy if you mix your weed with
tobacco as most of Europe does today.. but eating edibles or ingesting concetrates,BHO,RSO cant be in same category and i think this study dont covers this kind of users.
 
M

mGeRxOiWcEaRn

Do a little digging and you can find that it's all bogus.
Based on a search on Elisabeth Jorandby, M.D.,

Who works for http://www.amenclinics.com/home/

Looks like BS science based on the info found here: https://www.quackwatch.org/06ResearchProjects/amen.html


'The key question in evaluating a diagnostic test is whether or not its findings are useful in determining what treatment the patient should have. SPECT is a research tool useful for exploring how the brain functions, but the findings are nonspecific, and uses related to treatment of emotional or behavioral problems should be considered experimental. Dr. Amen has vast clinical experience and says he has performed and interpreted more than 35,000 scans. However, I do not believe he has demonstrated that specific scan patterns reliably reflect specific clinical problems and how they should be treated. Even when he is able to show a correlation between a diagnosis and an area of low perfusion (blood flow), he has not shown what this really means and how it could aid clinical treatment. Is low perfusion an indication of the primary pathology or perhaps just a secondary brain response to the symptoms? His published research comprises “preliminary studies,” and most psychiatrists believe it is premature to use SPECT clinically. In fact, the American Psychiatric Association (APA) has issued two skeptical reports, one pertaining to children and adolescents and the other pertaining to adults."
 

Popice

Member
not a scientist, but maybe the hippocampus could still have lower blood flow that relates to certain anxiety relief as the brain directs more blood through cannabinoid receptors. Like slowing "negative thought" areas from learned experiences while also slightly disassociating from present ["sense input"] which can give anxiety as well as block pain, while maintaining a sense of present where you either keep focus on the short block of time progressing forward or "overthink/get stuck" on the metaphysical (why/how) aspects of reacting in the present altered state. why without cognitive experience on something doing things are then harder than those that have become "back of hand." so a blood flow test for certain areas of the brain would leave out where the blood may redirect still leaving the "areas in question" to have a change in blood flow due to "however we want to twist" the results. this of course assumes that blood flow is what helps the brain function and process.
 

Tonygreen

Well-known member
ICMag Donor
Veteran
No, thats old age arid lmao

although i have locked my keys out of the house several times lol
 
Damn junk science studies everywhere nowadays putting agendas and sales ahead of the truth.. It's pretty sad but hey they paid for it they put forth an interpretation that works for them
 

angelgoob

Member
cool.

coffee/caffeine does this too. it seems the brain selects where it wants all the blood to flow better on cannabis and coffee. And the two go great together.

and to the person posting nootropics. i find focus formula from vitavalue a deal. vinpocentine and huperzine A. 30 pills for 5 doll hairs.
 

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