Very high CBD strains, which ones?

[SCF]

Sleepy effect from going longer is from more CBN. More amber trichomes will have the same effect.

CBD is ALL in the strain. Not anything else.

CBD also is something that Ripens Into the bud. From Drying, curing and processing. All these things will have a effect of how much CBD you can squeeze out of a plant. and im sure there is a big variation from Fresh Bud, to bud that has been cured for 6 months.

 

[SCF]

Humm .. CBD is nearly a stimulant.

Produces the "awake effect." Enhances memory. People lose weight.

I've tossed it at ADD kind of folks before and watched them snap to .. almost instantly.

Sooo .. probably not CBD.

Sounds like a good wallop of THC. Feathered by some nice quality turpenes. Maybe some delta 8 THC.

Another clue about CBD is onset/duration activities. CBD will delay the onset of THC and extend its duration.

But we're guessing.

im going to take back my statement. As it cures. it has become a Pure stimulant. Almost like i can play guitar like Jimi Hendrix! No joke, i sat down and played for 4 hours.... This stuff is amazing for Depression, and concentration. But honestly, no narcotic effect at all. I got pictures i should just post them. but this bong wont get out my hand after harvest LOL. I think when i posted that Point Of View of the Purple, i was smoking other strains, so i have to keep on curing, and keep on trying morning tokes! for the first hour.

Peace!

i wish there was a home test we could figure out....

Edit Edit: A patient who has not smoked in a long time is coming over. i am going to give them some of the Purple. And another strain, i find hard getting any "Hi" Effect, Yet they are both very very Sticky full of Resin. Peace! The green one is a Haze, she went 10 + weeks. So did the Purple. The Trichromes didnt form untill week 9ish, then really started to RISE like Mushrooms. so to speak. i have a third strain too. More like a Trainwreck smell, i harvested her the same time too basically.

All three from the same Seed Batch i got from a Old Time Smoke from the 60's!

 

[SCF]

confirmed. he said his first thoughts, he didnt want to insult me, but he didnt seem to be high. i think i will have to play with this strain. i need to get it tested. Lets see what he says about the Sativa that grew like Jack And The Bean Stalk. haze

 

[Bobo Bolinsky]

Here is some encouraging CBD news I just got off Alternet

But, based mostly on research overseas there is an increasing consensus that the medicinal benefits of psychoactive THC pale in comparison to the non-psychoactive cannabidiol (CBD) from the leaves of the same plant–raw and unheated. Depending on the strain, some plants are high in CBD but also contain a lesser amount of THC which is said to enhance the healing potentiality. CBD does not make people feel “stoned” and actually counters some of the effects of THC (for example, suppressing the appetite vs. stimulating it). CBD is beginning to be recognized by researchers at mainstream medical institutions around the world as a potentially very powerful weapon against cancer.

Researchers Sean D. McAllister and Pierre Desprez, who conducted studies of CBD’s effect on cancer cells for California Pacific Medical Center, suggest that these non-psychoactive compounds from the cannabis plant might, in short order, render chemotherapy and radiation distant second and third options for cancer patients. Based on a more recent study, McAllister and Desprez feel that CBD’s “could stop breast cancer from spreading.”

Dr. Donald Abrams, a cancer specialist and professor of integrative medicine at UCSF, conducted early trials involving THC medical cannabis, and now he is excited about the powerful impacts of CBD on cancer cells. The National Cancer Institute was busy researching this in the 1970s, Abrams explains, but restrictions on the use of cannabis for research in the United States resulted in most of the research on this subject disappearing in the U.S., and being picked up in other countries, such as Israel, Spain and Italy. He says existing studies point to a remarkable ability of CBD to arrest cancer cell division, cell migration, metastasis, and invasiveness.

Other studies point to CBD as having great promise as a defense against Alzheimer’s disease. In a 2006 study published in Molecular Pharmaceutics, a team of University of Connecticut researchers reported that cannabis “could be considerably better at suppressing the abnormal clumping of malformed proteins that is a hallmark of Alzheimer’s disease than any currently approved prescription.” The research team predicted that cannabinoid-based medications “will be the new breakout medicine treatments of the near future.”

 

[Sam_Skunkman]

This is wrong, CBDA totals do not increase by drying, curing or whatever. CBD % is controlled by genetics.
-SamS

CBD also is something that Ripens Into the bud. From Drying, curing and processing. All these things will have a effect of how much CBD you can squeeze out of a plant. and im sure there is a big variation from Fresh Bud, to bud that has been cured for 6 months.

 

[Sam_Skunkman]

Herbal Cannabis does not produce delta 8 THC, it is an artifact of analysis.
-SamS

Humm .. CBD is nearly a stimulant.

Produces the "awake effect." Enhances memory. People lose weight.

I've tossed it at ADD kind of folks before and watched them snap to .. almost instantly.

Sooo .. probably not CBD.

Sounds like a good wallop of THC. Feathered by some nice quality turpenes. Maybe some delta 8 THC.

Another clue about CBD is onset/duration activities. CBD will delay the onset of THC and extend its duration.

But we're guessing.

 

[Hammerhead]

Im trying to acquire some Z7..They say its over 8% CBD....

 

[village green]

Im trying to acquire some Z7..They say its over 8% CBD....

Just saw where Otto#1 is available in regular 12 packs. They claim some phenos have tested at 11% with less than 1% THC. I'm thinking the way to go might be to grow an all CBD plant and blend it with a high THC plant when smoking.

 

[danut]

Herbal Cannabis does not produce delta 8 THC, it is an artifact of analysis.
-SamS

Very interesting. I'll have to look into it better.

Nice to see you still posting.

 

[danut]

This is wrong, CBDA totals do not increase by drying, curing or whatever. CBD % is controlled genetics.
-SamS

Thank you. I don't think he would have believed me.

 

[Chimera]

This is wrong, CBDA totals do not increase by drying, curing or whatever. CBD % is controlled genetics.
-SamS

While I agree with you in that curing will not 'coax out' more CBD, it's not exactly true to say the CBDA level will not increase as the nugs dry.

This is one of the major problems with the testing labs, is that most do not express their methodology for reporting the percentages of the components.

For eg- if a client drops off some spongey nugs with say 15% water content and you immediately remove 50 mg of the sample for extraction and analysis, you will get a lower CBD/THC reading than if the flowers were very dry, or the lab dried the flowers over night say @ 30 deg Celsius pre-extraction, and then 50mg were taken for extraction and analysis.

Since the %'s are expressed as a factor of the original weight of the sample, the amount of water that is present in the flowers will reflect upon the final CBD/THC content expressed as a % by up to 10%.

Does curing/aging bring out more CBD/CBDa in the flowers over time? No absolutely not, as Sam states above.

Can the relative dryness of a flower influence the relative amount of CBD/THC expressed as a percentage of total weight in the sample? Yes absolutely.

To really compare %'s of active ingredients, it's really important that the flowers are treated in the same manner pre-analysis, and actually begin the analysis process from extraction onwards in the same physical state; for this reason it's really important that labs publish or make available their testing protocol so we can actually gain some meaningful numbers that we can interpret altogether... otherwise we are comparing apples to oranges.

-Chimera

 

[bowzer]

While I agree with you in that curing will not 'coax out' more CBD, it's not exactly true to say the CBDA level will not increase as the nugs dry.

This is one of the major problems with the testing labs, is that most do not express their methodology for reporting the percentages of the components.

For eg- if a client drops off some spongey nugs with say 15% water content and you immediately remove 50 mg of the sample for extraction and analysis, you will get a lower CBD/THC reading than if the flowers were very dry, or the lab dried the flowers over night say @ 30 deg Celsius pre-extraction, and then 50mg were taken for extraction and analysis.

Since the %'s are expressed as a factor of the original weight of the sample, the amount of water that is present in the flowers will reflect upon the final CBD/THC content expressed as a % by up to 10%.

Does curing/aging bring out more CBD/CBDa in the flowers over time? No absolutely not, as Sam states above.

Can the relative dryness of a flower influence the relative amount of CBD/THC expressed as a percentage of total weight in the sample? Yes absolutely.

To really compare %'s of active ingredients, it's really important that the flowers are treated in the same manner pre-analysis, and actually begin the analysis process from extraction onwards in the same physical state; for this reason it's really important that labs publish or make available their testing protocol so we can actually gain some meaningful numbers that we can interpret altogether... otherwise we are comparing apples to oranges.

-Chimera

This place is awesome!!! Where else can you go and have someone like Chimera giving advice?? To me it's like getting advice from Arnold Palmer on golf, or Michael Jordan on basketball, you get the idea... I am so thrilled to be learning from some of the best!!! Thank YOU

 

[SCF]

While I agree with you in that curing will not 'coax out' more CBD, it's not exactly true to say the CBDA level will not increase as the nugs dry.

This is one of the major problems with the testing labs, is that most do not express their methodology for reporting the percentages of the components.

For eg- if a client drops off some spongey nugs with say 15% water content and you immediately remove 50 mg of the sample for extraction and analysis, you will get a lower CBD/THC reading than if the flowers were very dry, or the lab dried the flowers over night say @ 30 deg Celsius pre-extraction, and then 50mg were taken for extraction and analysis.

Since the %'s are expressed as a factor of the original weight of the sample, the amount of water that is present in the flowers will reflect upon the final CBD/THC content expressed as a % by up to 10%.

Does curing/aging bring out more CBD/CBDa in the flowers over time? No absolutely not, as Sam states above.

Can the relative dryness of a flower influence the relative amount of CBD/THC expressed as a percentage of total weight in the sample? Yes absolutely.

To really compare %'s of active ingredients, it's really important that the flowers are treated in the same manner pre-analysis, and actually begin the analysis process from extraction onwards in the same physical state; for this reason it's really important that labs publish or make available their testing protocol so we can actually gain some meaningful numbers that we can interpret altogether... otherwise we are comparing apples to oranges.

-Chimera

Exactly, couldnt have explained it better myself. Water Weight has a HUGE effect on the amount of AVAILABLE Cannabinoids.
I believe, that the Trichomes themselves also retain water, this is why they look so huge on the plant, but when its dry, they look a lot smaller! not standing up straight etc.

You retain at least 5 percent more water, while you are curing. and depending on how long of a cure you do. Like i cure for awhile. Easy to do without molding, if done right, and attend to it. But when i dry them out, is when the real HIGH of the smoke kicks in. Probably a huge reason of why i am having a hard time getting high.

Water Weight means more than we think. i like my buds, bone dry.

Ever smoke a fresh bud ripe of the plant vs a bud that has cured and dried completely. Which one gets you higher? And i do not believe ALL cannabis strains are the same. There is so much Variation out there no 2 plants are the same.

Marijuana has over 100 Different Cannabinoids. Yet we focus on only a couple. We have a lot of research before we can say anything, Indefinite.

 

[Sam_Skunkman]

Cannabis does not have over 100 Cannabinoids, I think the total today is more like 85. The reason the focus has been on only a few is that they are the ones that get you high, THC, CBN, while CBD and THCV modify the effects of THC.
Now that the focus is also medical many more uses will be found for the other Cannabinoids like CBD, THCV, CBC, CBG, CBN as well as the acid forms of the Cannabinoids.

-SamS

Exactly, couldnt have explained it better myself. Water Weight has a HUGE effect on the amount of AVAILABLE Cannabinoids.
I believe, that the Trichomes themselves also retain water, this is why they look so huge on the plant, but when its dry, they look a lot smaller! not standing up straight etc.

You retain at least 5 percent more water, while you are curing. and depending on how long of a cure you do. Like i cure for awhile. Easy to do without molding, if done right, and attend to it. But when i dry them out, is when the real HIGH of the smoke kicks in. Probably a huge reason of why i am having a hard time getting high.

Water Weight means more than we think. i like my buds, bone dry.

Ever smoke a fresh bud ripe of the plant vs a bud that has cured and dried completely. Which one gets you higher? And i do not believe ALL cannabis strains are the same. There is so much Variation out there no 2 plants are the same.

Marijuana has over 100 Different Cannabinoids. Yet we focus on only a couple. We have a lot of research before we can say anything, Indefinite.

 

[SCF]

Cannabis does not have over 100 Cannabinoids, I think the total today is more like 85. The reason the focus has been on only a few is that they are the ones that get you high, THC, CBN, while CBD and THCV modify the effects of THC.
Now that the focus is also medical many more uses will be found for the other Cannabinoids like CBD, THCV, CBC, CBG, CBN as well as the acid forms of the Cannabinoids.

-SamS

well according to University of Saskatchewan it does.

Discovered Cannabis 'Pharma Factory'

University of Saskatchewan (U of S) researchers have discovered the chemical pathway that Cannabis sativa uses to create bioactive compounds called cannabinoids, paving the way for the development of marijuana varieties to produce pharmaceuticals or cannabinoid-free industrial hemp. The research appears online in the July 16 early edition of the Proceedings of the National Academy of Sciences (PNAS).

Cannabinoids are produced on the flowers of the female plant of Cannabis sativa in tiny hair-like structures called trichomes, the plant’s own "chemical factories."

Credit: Jon Page (UofS/NRC), Klaus Adler (IPK-Gatersleben, Germany)

U of S adjunct professor of biology Jon Page explains that the pathway is an unusual one, involving a specialized version of one enzyme, called hexanoyl-CoA synthetase, and another enzyme, called olivetolic acid cyclase (OAC), that has never before been seen in plants.

"What cannabis has done is take a rare fatty acid with a simple, six-carbon chain and use it as a building block to make something chemically complex and pharmacologically active," Page says.

Page led the research with PhD student Steve Gagne, who discovered OAC, and postdoctoral researcher Jake Stout, who discovered hexanoyl-CoA synthetase (reported earlier this year in The Plant Journal).


Hemp forms of Cannabis sativa are primarily grown in Canada for seed, which is produced on the female plants in this mixed plot. The seed has a healthy mix of omega 3 and 6 fatty acids is high in protein, and its oil is used in both food and cosmetic products.

Credit: Jan Slaski (Alberta Innovates: Technology Futures)




Cannabis has been cultivated for thousands of years for food, fibre, medicine and as a psychoactive drug. Cannabinoids such as delta-9-tetrahydrocannabinol, or THC, are produced on the flowers of the female plant in tiny hair-like structures called trichomes, the plant's own "chemical factories." The researchers used genomic analysis of isolated trichome cells to produce a catalog of the genes involved in cannabinoid production.

Page and his colleagues have already used the new enzymes to coax yeast to produce olivetolic acid, a key metabolic intermediate on the biochemical pathway that leads to cannabinoids.

"Now that we know the pathway, we could develop ways to produce cannabinoids with yeast or other microorganisms, which could be a valuable alternative to chemical synthesis for producing cannabinoids for the pharmaceutical industry," Page says.

There are more than 100 known cannabinoids, only a few of which have been explored for their possible medicinal uses. THC is the main psychoactive cannabinoid, responsible for the "high" sought by recreational users, as well as medicinal effects such as pain relief, nausea suppression and appetite stimulation. More than 19,000 patients in Canada are authorized to legally use marijuana to benefit from these effects, and many others use cannabinoid-containing drugs via prescription. Another important cannabinoid, cannabidiol (CBD) has anti-anxiety and neuro-protective properties.


University of Saskatchewan adjunct professor of biology Jon Page led the research team that discovered the chemical pathway Cannabis sativa uses to create bioactive compounds called cannabinoids.

Credit: University of Saskatchewan


Page explains that knowledge of the cannabinoid-making pathway could also make matters easier for Canadian farmers. Plant breeders can now look for cannabis strains that lack key parts of the cannabinoid-making pathway, which would allow for zero-THC varieties (current Canadian regulations call for no more than 0.3 per cent THC for industrial hemp, compared to 15 per cent or higher in the more potent marijuana varieties).

Although hemp cultivation in Canada dates back to the 1600s in Quebec, today industrial hemp is a niche crop, grown mostly on the Prairies. Its popularity fluctuates considerably, with about 15,700 hectares (39,000 acres) grown in 2011 according to statistics from Health Canada, which regulates the crop.

While hemp is well-known as a fibre crop for everything from textiles, rope and paper, it is more often grown in Canada for its seed. Hemp seed, which is high in omega-3 and omega-6 fatty acids, is marketed for its healthy qualities. It is used in everything from lactose-free hemp milk, breakfast cereals, snack foods and protein supplements for athletes. Hemp oil is also used in cosmetic skin care products.

Funding for this research was provided by the Natural Sciences and Engineering Research Council (NSERC), the Genome Canada PhytoMetaSyn project, Genome Prairie, Saskatchewan Ministry of Agriculture and the National Research Council.


Contacts and sources:
Michael Robin
University of Saskatchewan

http://nanopatentsandinnovations.blogspot.com/2012/07/discovered-cannabis-pharma-factory.html

 

[Sam_Skunkman]

I can tell you they are just plain wrong. The total today is now about 85 I believe.
-SamS

[Editor's Note: Mohamed M. Radwan, Mahmoud A. ElSohly, et al., researchers at the University of Mississippi, reported the discovery of nine new cannabinoids in their Apr. 3, 2009 study titled "Biologically Active Cannabinoids from High-Potency Cannabis Sativa," published in the Journal of Natural Products. This discovery brings the total number of cannabinoids to about 80, according to an Apr. 12, 2009 bulletin published by the International Association for Cannabis as Medicine.]

well according to University of Saskatchewan it does.

There are more than 100 known cannabinoids, only a few of which have been explored[/B][/SIZE] for their possible medicinal uses. THC is the main psychoactive cannabinoid, responsible for the "high" sought by recreational users, as well as medicinal effects such as pain relief, nausea suppression and appetite stimulation. More than 19,000 patients in Canada are authorized to legally use marijuana to benefit from these effects, and many others use cannabinoid-containing drugs via prescription. Another important cannabinoid, cannabidiol (CBD) has anti-anxiety and neuro-protective properties.


University of Saskatchewan adjunct professor of biology Jon Page led the research team that discovered the chemical pathway Cannabis sativa uses to create bioactive compounds called cannabinoids.

Contacts and sources:
Michael Robin
University of Saskatchewan

http://nanopatentsandinnovations.blogspot.com/2012/07/discovered-cannabis-pharma-factory.html

 

[Bobo Bolinsky]

Another area "ripe" for investigation is the medicinal aspects of terpenes in Cannabis as well as other edible fruits. Could be a lot more going on there than aromatics.

 

[SCF]

That report was from 2012. we have found MORE cannabinoids. I dont know why you haev to come out for a couple of years and pick out those two sentences i say about curing and cannabinoids, and just say im wrong without showing any proof.

I just gave you a article, where they Discovered Where Trichromes come from. so i think they have a understanding about trichomes.

Rodwin and Mississippi is old news.

Also it is believed that Marijuana has 421 ChemoTypes. What is a Chemotype you ask?

A chemotype (sometimes chemovar) is a chemically distinct entity in a plant or microorganism, with differences in the composition of the secondary metabolites. Minor genetic and epigenetic changes with little or no effect on morphology or anatomy may produce large changes in the chemical phenotype. Chemotypes are often defined by the most abundant chemical produced by that individual and the concept has been useful in work done by chemical ecologists and natural product chemists. With respect to plant biology, the term "chemotype" was first coined by Dr. Rolf Santesson and his son Johan in 1968, defined as, "...chemically characterized parts of a population of morphologically indistinguishable individuals."[1]

 

[SCF]

Just a few of the Cannabanoids.

(-)-[delta 1]-3,4-trans-tetrahydrocannabinol (most active cannabinoid)
(-)-[delta 6]-3,4-trans-tetrahydrocannabinol
tetrahydrocannabitriol (aka cannabitriol)
cannabidiolic acid
cannabidiol
cannabinol (forms after plant dies)
THC acids A and B (inactive unless smoked)

Minor constituents:

cannabigerol
cannabigerolic acid
cannabichromene
cannabichromenic acid
cannabicyclol (aka cannabipinol)
cannabicyclolic acid
cannabicitran
cannabielsoic acids A and B
cannabinolic acid (neutral cannabinoid)
cannabichromanon
cannabifuran
dehydrocannabifuran
2-oxo-[delta 3]-tetrahydrocannabinol
cannabigerol monomethyl ether
cannabidiol monomethyl ether
cannabinol methyl ether
propylcannabidiol (aka cannabidivarol & cannabidivarin)
propylcannabinol (aka cannabivarol & cannabivarin)
propyl-[delta 1]-THC (aka [delta 1]-tetrahydrocannabivarol & tetrahydrocannabivarin)
propylcannabigerol
propylcannabicyclol
propylcannabichromene
methylcannabidiol (aka cannabidiorcol)
methylcannabinol (aka cannabiorcol)
methyl-[delta 1]-THC (aka [delta 1]-tetrahydrocannabiorcol)
[delta 1]-tetrahydrocannabivarolic acid
Nitrogen-containing compounds:

choline
trigonelline
muscarine
piperidine
N-(p-hydroxy-B-phenylethyl)-p-hydroxy-trans-cinnamide
neurine
L-proline
L-isoleucine betaine
hordenine
cannabisativine (alkaloid found in the roots)

[compiled from "The Botany and Chemistry of Hallucinogens" by Schultes & Hofmann]

 

[SCF]

Another very well Accredited Cannabinoids Researchers and focus ONLY on Cannabinoids.

Name is Abatin, they are based out of Sacramento.

What We Do
Abatin Wellness Center operates as a true cooperative where medical cannabis patients, assisted by trained counselors and staff, work together to create the next generation of herbal cannabis medicines. Abatin Wellness provides a unique counseling approach that helps its members identify the most effective cannabis strains and delivery methods to meet each member’s individual needs. Members are also encouraged to provide feedback during each visit to help Abatin improve the quality and effectiveness of its cannabis medicines. At Abatin Wellness, members can also access hundreds of published studies, articles and books encompassing the latest cannabis research from around the globe. From cannabinoid and terpenoid assays to pathogen, pesticide and mold screening, Abatin oversees the most comprehensive medical cannabis quality assurance program in California. We provide this testing information to our members to share with their physicians, so that their doctors can assist with designing more precise strategies for using cannabis medicinally.



Over 100 phytocannabinoids have been identified but most are produced in trace quantities that have not permitted thorough investigation. This is a look at several of the common phytocannabnoids and their pharmacological effects.