found this on cc forum. way over my head, but seems interesting:
For you chemists out there here is the real formula to make synthetic THC!!!
THC. A mixture of 2.9 g of olivetol (or analog) and 2.5 g of (+)-cis/trans-p-menthadienol,
and 2 g of anhydrous magnesium sulfate is stirred with 100 ml of methylene chloride under a
nitrogen atmosphere. After cooling in an ice bath, 1 ml of freshly distilled BF3-Et20 is added. The
mixture is stirred for 1 lh. hours at 0° and 5 g of anhydrous sodium bicarbonate is added and stirred
until the color fades. The reaction mixture is filtered and evaporated to give 5 g of a colorless
gum containing 50% delta 1 THC. I feel that if this is to be used by smoking it does not need
to be purified further, however, this is the process for complete purification: 3 g of the above gum
is chromotagraphed on 150 g of 100-200 mesh Florisil that is packed in a 1 inch by 36 inch
column in petroleum ether at 30-40°. Elute with graded mixtures up to 2 parts ether to 98 parts
petroleum ether to yield .75 g of pure product.
Olivetol and its analogs can be obtained from lichen, a moss-like substance which grows on many trees. (+)-cis/trans-p-menthadienol can be extracted from moldy orange peels by dissolving it in an appropriate solvent, such as ethanol, and evaporating. The orange peels have to be moldy, because (+)-cis/trans-p-menthadienol is syntesized by the mold from limonene, which is found in orange peels.
BF3-Et20 can be replaced by any Lewis acid, such as Aluminum Trichloride (AlCl3).
Source: THC&TROPOCOCAINE by Otto Snow
For you chemists out there here is the real formula to make synthetic THC!!!
THC. A mixture of 2.9 g of olivetol (or analog) and 2.5 g of (+)-cis/trans-p-menthadienol,
and 2 g of anhydrous magnesium sulfate is stirred with 100 ml of methylene chloride under a
nitrogen atmosphere. After cooling in an ice bath, 1 ml of freshly distilled BF3-Et20 is added. The
mixture is stirred for 1 lh. hours at 0° and 5 g of anhydrous sodium bicarbonate is added and stirred
until the color fades. The reaction mixture is filtered and evaporated to give 5 g of a colorless
gum containing 50% delta 1 THC. I feel that if this is to be used by smoking it does not need
to be purified further, however, this is the process for complete purification: 3 g of the above gum
is chromotagraphed on 150 g of 100-200 mesh Florisil that is packed in a 1 inch by 36 inch
column in petroleum ether at 30-40°. Elute with graded mixtures up to 2 parts ether to 98 parts
petroleum ether to yield .75 g of pure product.
Olivetol and its analogs can be obtained from lichen, a moss-like substance which grows on many trees. (+)-cis/trans-p-menthadienol can be extracted from moldy orange peels by dissolving it in an appropriate solvent, such as ethanol, and evaporating. The orange peels have to be moldy, because (+)-cis/trans-p-menthadienol is syntesized by the mold from limonene, which is found in orange peels.
BF3-Et20 can be replaced by any Lewis acid, such as Aluminum Trichloride (AlCl3).
Source: THC&TROPOCOCAINE by Otto Snow
