Scientists have found that memories may be passed down through generations in our DNA

[Weird]

I have suspected as much for a long time and have mentioned the prospect here several times (sure people with enough psychedelic experience will have the same suspicions )

http://www.sciencegymnasium.com/2014/01/scientists-have-found-that-memories-may.html

New research from Emory University School of Medicine, in Atlanta, has shown that it is possible for some information to be inherited biologically through chemical changes that occur in DNA. During the tests they learned that that mice can pass on learned information about traumatic or stressful experiences – in this case a fear of the smell of cherry blossom – to subsequent generations.

​

According to the Telegraph, Dr Brian Dias, from the department of psychiatry at Emory University, said: ”From a translational perspective, our results allow us to appreciate how the experiences of a parent, before even conceiving offspring, markedly influence both structure and function in the nervous system of subsequent generations.

“Such a phenomenon may contribute to the etiology and potential intergenerational transmission of risk for neuropsychiatric disorders such as phobias, anxiety and post-traumatic stress disorder.”

This suggests that experiences are somehow transferred from the brain into the genome, allowing them to be passed on to later generations.

The researchers now hope to carry out further work to understand how the information comes to be stored on the DNA in the first place.

They also want to explore whether similar effects can be seen in the genes of humans.

Professor Marcus Pembrey, a paediatric geneticist at University College London, said the work provided “compelling evidence” for the biological transmission of memory.

He added: “It addresses constitutional fearfulness that is highly relevant to phobias, anxiety and post-traumatic stress disorders, plus the controversial subject of transmission of the ‘memory’ of ancestral experience down the generations.

“It is high time public health researchers took human transgenerational responses seriously.

“I suspect we will not understand the rise in neuropsychiatric disorders or obesity, diabetes and metabolic disruptions generally without taking a multigenerational approach.”

Professor Wolf Reik, head of epigenetics at the Babraham Institute in Cambridge, said, however, further work was needed before such results could be applied to humans.

He said: “These types of results are encouraging as they suggest that transgenerational inheritance exists and is mediated by epigenetics, but more careful mechanistic study of animal models is needed before extrapolating such findings to humans.”

May our DNA Carrying also spiritual and cosmic memories passed down in genes from our ancestors ?
- See more at: http://www.sciencegymnasium.com/201...d-that-memories-may.html#sthash.vFoto52M.dpufhttp://www.sciencegymnasium.com/201...d-that-memories-may.html#sthash.vFoto52M.dpuf

 

[5th]

I thought blaming everything on your parents died out in the 90's?

And who the fuck send's "telegraph's" anymore?

Love reading your post's Weird...but I'm calling bullshit on this one.

 

[Weird]

its THE telegraph (a newspaper) and there is some science behind this one

Parental olfactory experience influences behavior and neural structure in subsequent generations

http://www.nature.com/neuro/journal/v17/n1/full/nn.3594.html

Using olfactory molecular specificity, we examined the inheritance of parental traumatic exposure, a phenomenon that has been frequently observed, but not understood. We subjected F0 mice to odor fear conditioning before conception and found that subsequently conceived F1 and F2 generations had an increased behavioral sensitivity to the F0-conditioned odor, but not to other odors. When an odor (acetophenone) that activates a known odorant receptor (Olfr151) was used to condition F0 mice, the behavioral sensitivity of the F1 and F2 generations to acetophenone was complemented by an enhanced neuroanatomical representation of the Olfr151 pathway. Bisulfite sequencing of sperm DNA from conditioned F0 males and F1 naive offspring revealed CpG hypomethylation in the Olfr151 gene. In addition, in vitro fertilization, F2 inheritance and cross-fostering revealed that these transgenerational effects are inherited via parental gametes. Our findings provide a framework for addressing how environmental information may be inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels.

 

[Coconutz]

Its called roots homie!

I can remember in my mind
Way back before my time
A memory lived through my DNA line
And I can see it in Jah sign
That we could be just fine
Let history reveal the truths we need to find
But the memories are long gone
Forgotten truths hid from the youths
Through many years by Babylon so
So we sing it in this song
With hopes to resurrect consciousness
Back through our daughters and our sons yeah

 

[Sam_Skunkman]

Sure "environmental information "may be" inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels."

Or maybe not.

And when you are high on acid you know there is a god because you can sense him, right?
Or maybe it is just your right half of the brain sensing the left half?
When you take psychedelics your brain alters from the normal dominate left to the right.
The left side of the brain is the seat of language and processes in a logical and sequential order. The right side is more visual and processes intuitively, holistically, and randomly.
Cannabis also does this to a degree.
But I do agree that if you sense god the information "may be" inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels."
Just ask any Jesus, Mohammad, YHWH, Hindu, or Buddhist freak, they know the truth...
-SamS

 

[Weird]

lol nice tangent sam

if environmental information were not inherited how would and why would organisms be dynamic (evolve) instead of simply stay static (stay the same)

attack the science sam. not that i dont mind a little give and go and i guess you owe me one but remember all my reasoning is based in very sound logic and I can defend any of it and quite well

why not tell us your theory of why environmental information is NOT inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels

or will you take the typical " I discovered through the use of science in a laboratory long ago what the answer to this question is but i cannot share it with the world at this time"

 

[Weird]

darwin observed evolution over the course of a generation

what prompted that genetic adaptation? gene pairings?

there are other inputs that shape genes other than the genes themselves we may not have them quantified or qualified completely but the evidence for them does exist

 

[Weird]

how did creatures evolve from living in the sea to living on land

how did they slowly over subsequent generations adapt to new environments if there was no mechanism to remember changes in the environment through dna

it also would be reasonable to believe that over time remembered changes in environment force phenotype variation relative to those environmental changes

 

[justpassnthru]

Interesting! I just hate it when they make me run on all 4z in that wheelie thingie and enjoy my mousie childhood over and over again! Just makes me wanna click the left side of the mouse and evolve already!

Kidding aside, as a very young toddler & thru early adulthood, I had nightmares of a very certain time, on a farm. The last time I had that dream, I received a phone call...my father passed. 3 days later I was on the family homestead farm in Oklahoma and that was the farm that was in my dreams from childhood. As a child, I never went to Oklahoma and no pictures of it existed. I was 30 when I saw that farm, I haven't had the nightmare since-evolution, 2 feet instead of 4z! jpt

 

[Hash Zeppelin]

I remember this one time back in 1776 when my, great grandfather (to the 5th power) cracked the liberty bell.

 

[LEF]

I am not surprised

in my mind I often thought about trauma as something that can have repercussions on generations

 

[BakedBandit]

I've always felt this to be true on some level. Glad I'm not alone

 

[BlueBlazer]

This explains my innate fear of Tyrannosaurus Rex.

 

[Sam_Skunkman]

Well the fact is we are all evolving all the time. It is called mutation.
We have slightly different progeny that have either an advantage or not, when they do have an advantage they multiply and soon take over, like Homo Sapiens did 2000,000 years ago.
Evolution works through mutation. Mutation is the source of all new genes and subsequently all new traits.
Epigenetics changes constitute true Lamarckian inheritance, i.e., the inheritance of acquired characteristics.
And lots of studies show us that Lamarckian inheritance doesn’t operate. Changes that are induced by the environment, or the organism’s “striving,” can’t somehow get incorported into the DNA. An athlete, for example, doesn’t produce kids with bigger muscles. And after millennia of circumcision, Jewish boys are still obstinately born with foreskins.
Nevertheless, there is a vocal subset of biologists who see the “Lamarckian” form of epigenetics as of great importance in evolution: a neglected area that is truly non-neo-Darwinian. This claim rests solely on a few studies showing that epigenetic change in DNA induced by the environment can sometimes be passed on for several generations. But there’s no evidence that this has produced any adaptive features of organisms.
I write about epigenetics at length because I think we need to understand the claim that discoveries in epigenetics show that modern evolutionary theory is either wrong or incomplete. This claim, which is wrong, often rests on a confusion between the adaptive methylation of DNA that is itself coded for by the DNA, and evolved by natural selection, and the nonadaptive methylation of DNA that occurs by effects of the environment.

In other words you do not need to remember environmental changes through DNA. If a DNA mutation confers an advantage it will thrive. Still wondering how did creatures evolve from living in the sea to living on land?
-SamS

how did creatures evolve from living in the sea to living on land

how did they slowly over subsequent generations adapt to new environments if there was no mechanism to remember changes in the environment through dna

it also would be reasonable to believe that over time remembered changes in environment force phenotype variation relative to those environmental changes

 

[Weird]

Well the fact is we are all evolving all the time. It is called mutation.
We have slightly different progeny that have either an advantage or not, when they do have an advantage they multiply and soon take over, like Homo Sapiens did 2000,000 years ago.
Evolution works through mutation. Mutation is the source of all new genes and subsequently all new traits.
Epigenetics changes constitute true Lamarckian inheritance, i.e., the inheritance of acquired characteristics.
And lots of studies show us that Lamarckian inheritance doesn’t operate. Changes that are induced by the environment, or the organism’s “striving,” can’t somehow get incorported into the DNA. An athlete, for example, doesn’t produce kids with bigger muscles. And after millennia of circumcision, Jewish boys are still obstinately born with foreskins.
Nevertheless, there is a vocal subset of biologists who see the “Lamarckian” form of epigenetics as of great importance in evolution: a neglected area that is truly non-neo-Darwinian. This claim rests solely on a few studies showing that epigenetic change in DNA induced by the environment can sometimes be passed on for several generations. But there’s no evidence that this has produced any adaptive features of organisms.
I write about epigenetics at length because I think we need to understand the claim that discoveries in epigenetics show that modern evolutionary theory is either wrong or incomplete. This claim, which is wrong, often rests on a confusion between the adaptive methylation of DNA that is itself coded for by the DNA, and evolved by natural selection, and the nonadaptive methylation of DNA that occurs by effects of the environment.

In other words you do not need to remember environmental changes through DNA. If a DNA mutation confers an advantage it will thrive. Still wondering how did creatures evolve from living in the sea to living on land?
-SamS

then how do you explain this?

[FONT=Arial, Helvetica, sans-serif]Parental olfactory experience influences behavior and neural structure in subsequent generations

http://www.nature.com/neuro/journal/...l/nn.3594.html

Using olfactory molecular specificity, we examined the inheritance of parental traumatic exposure, a phenomenon that has been frequently observed, but not understood. We subjected F0 mice to odor fear conditioning before conception and found that subsequently conceived F1 and F2 generations had an increased behavioral sensitivity to the F0-conditioned odor, but not to other odors. When an odor (acetophenone) that activates a known odorant receptor (Olfr151) was used to condition F0 mice, the behavioral sensitivity of the F1 and F2 generations to acetophenone was complemented by an enhanced neuroanatomical representation of the Olfr151 pathway. Bisulfite sequencing of sperm DNA from conditioned F0 males and F1 naive offspring revealed CpG hypomethylation in the Olfr151 gene. In addition, in vitro fertilization, F2 inheritance and cross-fostering revealed that these transgenerational effects are inherited via parental gametes. Our findings provide a framework for addressing how environmental information may be inherited transgenerationally at behavioral, neuroanatomical and epigenetic levels. [/FONT]

 

[Weird]

Memories of positive associations get written onto DNA

Epigenetic changes in nerve cells keep memories in place.

http://arstechnica.com/science/2013/08/memories-of-positive-associations-get-written-onto-dna/

Scientific Method / Science & Exploration
Memories of positive associations get written onto DNA
Epigenetic changes in nerve cells keep memories in place.

by John Timmer - Aug 26 2013, 5:00pm EDT

Life Sciences
40 Oak Ridge National Lab

Nerve cells communicate through short, fleeting pulses of electrical activity. Yet some memories stored in the brain can persist for decades. Research into how the nervous system bridges these two radically different time scales has been going on for decades, and a number of different ideas have picked up some experimental support.

For instance, based on their past activity, nerve cells can dictate which partners they make contact with or increase or decrease the strength of those connections—in essence, rewiring the brain as it develops and processes experiences. In addition, individual cells can make long-term changes in the genes that are active, locking specific behaviors in place. In a paper released by Nature Neuroscience, scientists have looked at the changes in gene expression associated with memories of positive associations and found that they are held in place by chemical modifications of the cells' DNA.

These chemical modifications fall under the broad (and somewhat poorly defined) category of epigenetic changes. Genetic changes involve alterations of the DNA sequence itself. Epigenetic changes, in contrast, alter how that DNA is processed within cells. They can be inherited as the cell divides and matures and, in rare cases, they're passed on to the next generation. In some cases, epigenetic changes simply involve how the DNA is packaged inside a cell, which controls how accessible it is to the enzymes that transcribe it for use in making proteins. But in other cases, the DNA itself is chemically modified. That changes how various proteins interact with it.

The most common of these chemical modifications is called methylation, where a single carbon atom is attached at a specific location on one of the DNA bases. A number of studies suggest that methylation changes accompany the formation of long-term memories, so the researchers decided to test this in a well characterized experimental system that dates back to Pavlov: teaching a mouse to associate a sound with having a sugary treat appear in its cage. (Controls included playing the tone in a way that it wasn't associated with treats and simply providing the tone.)

It only takes mice three tries before they start sniffing around the locations where the treat appears, and by five iterations, the behavior is pretty much locked-in. Past work in other systems has identified areas of the brain that are involved in this process, as well as some of the genes that are required. So, the authors started looking at how these changes came about when the association between the tone and a treat was being formed.

The researchers were able to confirm that the genes identified in past studies were involved in the formation of associative memories, and changes in the gene activity were detectable by the third trial just as behavior started to change. They were also able to detect significant changes in the DNA methylation that occurred at the same time, although only at a specific subset of the areas known to be methylated in that area of the chromosome. They were even able to show that the enzymes responsible for modifying the DNA appeared at these sites at around the time of the third trial.

All of that indicates that methylation changes are associated with the learning process, but it doesn't get at the issue of cause and effect. So, the team injected a chemical that blocks DNA methylation into the area of the brain that's involved with this form of associative memory, and they found that it would leave existing memories intact while blocking the formation of new ones. The effect was also specific to injections in this area of the brain. Injecting the drug into a different area, one that is involved in forming the associations involved in addiction, did not affect this particular form of memory.

Overall, the study adds another example to the growing list of cases where epigenetic changes seem to be involved in the process of locking memories into place. This doesn't mean that the memories are permanent, as there are enzymes that can eliminate methylation as well. Still, it should help maintain the status of the memories for long periods of time—far longer than a brief burst of activity.

But it's important to note that this sort of methylation is very context dependent: it's specific to a subset of cells in a single area of the brain. Different methylation patterns—or even the same methylation pattern in a different set of cells—will probably encode something very different.

Nature Neuroscience, 2013. DOI: 10.1038/nn.3504 (About DOIs).

 

[Sam_Skunkman]

If you reread my post you realize that most methylation changes are transitory they do not last more then a few generations at most.
But I think you know this.
-SamS

then how do you explain this?

 

[Weird]

f you reread my post you realize that most methylation changes are transitory they do not last more then a few generations at most.
But I think you know this.
-SamS

if one mechanism exists that allows for the environment to effect dna over a generation why would it be impossible to believe there is another or more to it than we have currently uncovered?

how do you think life evolved in a manner were it's success was relative to the environment it is born into?

or can you find me an example were it is not?

 

[Sam_Skunkman]

if one mechanism exists that allows for the environment to effect dna over a generation why would it be impossible to believe there is another or more to it than we have currently uncovered?

SURE ANYTHING IS POSSIBLE, BUT LETS WAIT UNTIL IT IS SHOWN THIS IS TRUE AND THAT IT DOES AFFECT HUMANS OVER MANY GENERATIONS.

how do you think life evolved in a manner were it's success was relative to the environment it is born into?

TRY AND REPHRASE YOUR QUESTION, I DO NOT UNDERSTAND IT.

or can you find me an example were it is not?

-SamS

 

[Weird]

do you think life evolved in a manner were it's success was relative to the environment it is born into?

What I am saying is that life evolved so it would continue to be successful in its current environment or it moved to one it could succeed in or it simply die out

success is contingent on environmental adaptation

you cannot adapt/evolve over generations without memory or those changes would have no relative context. everything that has evolved has evolved with purpose, the most obvious being environmental adaptation.

the organisms that live off of sulfur plumes from the underwater volcanoes are one example

there are creatures that have adapted/evolved along with the environment and there is a mechanism at place that is causing it

how does a plant evolve to create a chemical to aid it against predators? does it not have to have environmental interaction and doesn't that interaction have to change the dna for it to manifest as a physiological change?