Powdery Mildew from Hell!!

[Darkstarlive]

I've been battling PM for over 5 months, ever since the spring. I never had it before in the 6+ years I've been growing.
I've added 2 more fans and 1 more dehuey, My RH is 37% and I still get PM though mostly now its on the small bud leaves not so much the big fan leaves.
I spray with JMS stylet oil but it keeps coming back, I don't know what else I can do?

I have a sulphur burner but I'm hesitant to use it in my basement, I dont want to stink out my house with sulphur.
WTF!!!
Its been so god damn wet here on the eastcoast, will it disappear when the weather turns cold and we get some below freezing temps?

Peace...

 

[krunchbubble]

if you want to get rid of pm once and for all try eagle 20 ew. only use it once and NEVER have powder mildew again! its not a band aid like sulfur, this stuff gets rid of it....

 

[Hazyfontazy]

if you want to get rid of pm once and for all try eagle 20 ew. only use it once and NEVER have powder mildew again! its not a band aid like sulfur, this stuff gets rid of it....

got a link ,thanks

 

[2broke2smoke]

that Eagle 20ew says u got to apply every 7 to 10 days, that does not sound like anything more than a band aid to me.

2b2s

 

[SicKSKills]

Once you have PM it will never be totally gone, even with eagle20(systemic fungicide), which is far and away the best solution, you will still have to reapply once or twice a year to mother stock to keep it at bay...either way i dip all my clones in it before their final transplant because i dont want to ever see pm in my room, and even then it occasionally pops up on more susceptible strains like the kushes.

 

[Bobby Stainless]

JMS is some bullshit, when it comes to PM.

 

[jyme]

yea it has been really wet in the south east. and ive found that milk kills that lil devil rose farmers have been using it for years take a sprayer and mist them with it allow to set for a few then i remist with water to wash it off but it can be allowed to stay on them and its organtic so no poisons

 

[krunchbubble]

that Eagle 20ew says u got to apply every 7 to 10 days, that does not sound like anything more than a band aid to me.

2b2s

its systemic, stays in the plant for 30+ days. is just known around here, have powder mildew, use eagle 20 and you wont have it again. works perfectly...

 

[Darkstarlive]

I just checked out that Eagle 20EW.
Wow, thats some heavy shit.
Its a pretroleum distilate. It builds up a tolerence so they recommend using a rotation of fungicides. It has a 24hr REI.
Even though its used for stone fruit and grapes certain other things are not recommended for consummtion, like sunflower seeds.

Its sound good being systemic but I would be a little worried using it.

Thanks.

 

[johnnyla]

what does it taste like if dried flowers have powdery mildew. i just smoked some herb that tasted slightly moldy. how can you tell?

 

[sarek]

http://www.inchem.org/documents/jmpr/jmpmono/v92pr13.htm


Eagle is MYCLOBUTANIL


COMMENTS

Myclobutanil was rapidly absorbed when administered orally to
rats and mice. The principal routes of excretion were via the urine
and faeces, with no significant residual tissue accumulation. The
toxicokinetic model in the rodent did not differ markedly with
respect to species, sex, single versus repeated exposures or doses.

In both the rat and mouse, myclobutanil was extensively
metabolized to more polar compounds. The proposed metabolic pathway
of myclobutanil in the rat was through oxidation of the butyl group.
The major excretory metabolites were qualitatively similar with
respect to sex and dose.

Myclobutanil was only slightly toxic upon acute oral
administration to rats and mice. WHO has classified myclobutanil as
slightly hazardous (WHO, 1992).

The primary target organ upon repeated dietary exposure to
myclobutanil was the liver. Histomorphological changes,
characterized predominantly by centrilobular hepatocytic hypertrophy
in association with increased liver weights, were observed in all
species investigated. Microscopically, there was accentuated lobular
architecture, hepatocytic vacuolation, inflammation, necrosis, and
pigmentation of the Kupffer cells. Increased hepatic enzyme activity
in serum (ALAT, ASAT, GGT, ALP) were also observed. Hepatic
microsomal MFO activities in rats and mice were increased
correspondingly. There were no similar increases in hepatic
peroxisomal œ-oxidation activity that would have suggested
peroxisomal proliferation.

A three-month dietary study with myclobutanil in the mouse at
levels of 0, 3, 10, 30, 100, 300, 1000, 3000 or 10 000 ppm revealed
hepatic alterations at dietary levels of 1000 ppm and higher,
resulting in a NOAEL of 300 ppm, equal to 42.1 mg/kg bw/day.

Two 3-month studies in rats fed myclobutanil at levels of 0,
10, 30, 100, 300, 1000, 3000, 10 000, or 30 000 ppm and 0, 100, 300,
or 3000 ppm indicated a NOAEL of 100 ppm, equal to 5.2 mg/kg bw/day,
based on treatment-related hepatic effects.

The NOAEL for myclobutanil-related liver effects in dogs
treated for 3 months at 0, 10, 200, 800 or 1600 ppm was 10 ppm,
equal to 0.3 mg/kg bw/day. Treatment of dogs with myclobutanil for
12 months at dietary levels of 0, 10, 100, 400, or 1600 ppm resulted
in a NOAEL for hepatic effects of 100 ppm, equal to 3.1 mg/kg
bw/day. Myclobutanil administered to two dogs per sex at dietary
levels of up to 1000 ppm, equal to 39 mg/kg bw/day, did not produce
any hepatic changes after a period of 4 weeks.

Long-term dietary treatment of mice with myclobutanil for two
years at 0, 20, 100 or 500 ppm revealed a NOAEL of 20 ppm, equal to
2.7 mg/kg bw/day, based on increased MFO activity at 100 ppm as well
as more pronounced liver toxicity at 500 ppm and above. Myclobutanil
was not carcinogenic in mice.

A 24-month long-term toxicity/carcinogenicity study in rats at
dietary concentrations of 0, 50, 200 or 800 ppm revealed a NOAEL of
50 ppm, equal to 2.5 mg/kg bw/day, based on findings of testicular
atrophy and increased MFO activity at 200 ppm and above.
Myclobutanil was not carcinogenic in rats.

A two-generation reproduction study in rats at dietary
concentrations of 0, 50, 200 or 1000 ppm revealed a NOAEL of 50 ppm,
equal to 3.6 mg/kg bw/day, based on increased liver weights and an
increase in numbers of stillborn pups at 200 ppm and above. At 1000
ppm atrophy of the testes and prostate were observed.

An oral teratogenicity study in rats at gavage doses of 0, 31,
94, 310, or 470 mg/kg bw/day demonstrated clinical signs of toxicity
at 310 mg/kg bw/day and above, indicating a NOAEL of 94 mg/kg
bw/day. The NOAEL for embryofetal toxicity was 31 mg/kg bw/day.
There was no evidence of teratogenicity at doses up to 470 mg/kg
bw/day.

Myclobutanil was not teratogenic when administered to the
rabbit at gavage doses of 20, 60 or 200 mg/kg bw/day. A NOAEL for
maternal toxicity was 20 mg/kg bw/day, based on decreased body-
weight at 60 mg/kg bw/day and above. Embryofetal toxicity was
evident at 200 mg/kg bw/day.

After reviewing the available genotoxicity data, the Meeting
concluded that myclobutanil was not genotoxic.

An ADI was allocated on the basis of NOAELs in two-year feeding
studies in mice and rats, a reproduction study in rats and a one-
year study in dogs, using a 100-fold safety factor.

TOXICOLOGICAL EVALUATION

Level causing no toxicological effect

Mouse: 20 ppm, equal to 2.7 mg/kg bw/day (two-year study)

Rat: 50 ppm, equal to 2.5 mg/kg bw/day (two-year study)
50 ppm, equal to 3.6 mg/kg bw/day (two-generation
reproduction study)

Dog: 100 ppm, equal to 3.1 mg/kg bw/day (one-year study)

Estimate of acceptable daily intake for humans

0 - 0.03 mg/kg bw

Studies which will provide information valuable in the continued
evaluation of the compound

1. Results of ongoing long-term studies in mice and rats
known to be in progress.

2. If the results of (1) show a carcinogenic response,
studies (a) to determine whether myclobutanil acts as a
tumour promoter in the two-stage rat liver bioassay and
(b) whether it causes inhibition of intercellular
communications.

3. Observations in humans.

 

[sarek]

MYCLOBUTANIL

Fungicide
FRAC 3; DMI: triazole

MYCLOBUTANIL

NOMENCLATURE
Common name myclobutanil (BSI, ANSI, draft E-ISO, (m) draft F-ISO)
IUPAC name 2-p-chlorophenyl-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile; 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile
Chemical Abstracts name a-butyl-a-(4-chlorophenyl)-1H-1,2,4-triazole-1-propanenitrile
CAS RN [88671-89-0] Development codes RH-3866 (Rohm & Haas)

PHYSICAL CHEMISTRY
Mol. wt. 288.8 M.f. C15H17ClN4 Form Pale yellow solid. M.p. 63-68 ºC (tech.) B.p. 202-208 ºC/1 mmHg V.p. 0.213 mPa (25 ºC) KOW logP = 2.94 (pH 7-8, 25 ºC) Henry 4.33 × 10-4 Pa m3 mol-1 (calc.) Solubility In water 142 mg/l (25 ºC). Soluble in common organic solvents, e.g. ketones, esters, alcohols and aromatic hydrocarbons, all 50-100 g/l. Insoluble in aliphatic hydrocarbons. Stability Stable under normal storage conditions. Aqueous solutions decompose on exposure to light, DT50 222 d (sterile water), 0.8 d (sensitised sterile water), 25 d (pond water); no hydrolysis (28 ºC) in 28 d (pH 5, 7, and 9).

APPLICATIONS
Biochemistry Inhibits ergosterol biosynthesis (steroid demethylation inhibitor). Mode of action Systemic fungicide with protective and curative action. Uses Control of Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops. For example, used as a foliar treatment for control of scab and powdery mildew in apples and pears; powdery mildew, shot-hole, blossom blight, and rust in stone fruit; powdery mildew in vines and cucurbits; powdery mildew and rusts on ornamentals; rusts on perennial grasses grown for seed; and various diseases of wheat; as a seed treatment for control of seed- and soil-borne diseases in barley, maize, cotton, rice and wheat; and as a post-harvest drench or dip. Formulation types EC; SC; WP; Seed treatment.

ANALYSIS
Product by gc. Residues by gc. Details from Rohm & Haas.

MAMMALIAN TOXICOLOGY
Reviews FAO/WHO 65, 67 (see part 2 of the Bibliography). Oral Acute oral LD50 for male rats 1600, female rats 2290 mg/kg. Skin and eye Acute percutaneous LD50 for rabbits >5000 mg/kg. Not irritating to their skin but mildly to their eyes; not a skin sensitiser to guinea pigs. NOEL (90 d) for rats and female dogs 100, male dogs 10 mg/kg diet. No reproductive effects were observed in rats at 200 mg/kg, but there were some reproductive effects in male rats at 1000 mg/kg. ADI (JMPR) 0.03 mg/kg b.w. [1992]. Other Non-teratogenic in rats and rabbits, and various mutagenicity tests proved negative. Not mutagenic in the Ames assay. Toxicity class WHO (a.i.) III EC hazard R63| Xn; R22| Xi; R36| N; R51, R53

ECOTOXICOLOGY
Birds Acute oral LD50 for bobwhite quail 510, grey partridges 1635 mg/kg. Fish LC50 (96 h) for bluegill sunfish 2.4, rainbow trout 4.2 mg/l. Daphnia LC50 (48 h) 11 mg/l. Bees Non-toxic to bees.

ENVIRONMENTAL FATE
Animals In animals, undergoes oxidation at the butyl group to a ketone and an alcohol, with partial conjugation to a glucoside. Following oral administration, rapidly excreted in the faeces and urine. Plants In plants, metabolism is the same as in animals. Soil/Environment In soil, DT50 66 d (silt loam). Decomposition is through highly polar triazole compounds, with further degradation by ring splitting. No degradation under anaerobic conditions.

 

[mk6]

thanks for the read but;
"Myclobutanil was rapidly absorbed when administered orally to
rats and mice."

Orally is not smoking it.... smoking it as hits your lungs, BAD! so I dont think their study applies to us.

 

[VagPuncher]

Meltatox.

Chimera spoke of it and I have never seen PM again.

 

[ButteredIt]

I'm not sure of the rules and citing where I got this, but it's relevant here and useful. Cleared up a lot of my questions about PM and the treatment of.

"Powdery Mildew (PM) is a systemic problem coming from within an infected plant. What you are seeing (the white powderey looking substance) on the leaves is the flowering body of the fungus- the hyphae live within the plant. By the time you can visually identify the problem it's already well established within the plant. No external treatment (like sulphur) can fix the problem.

PM proliferates in shaded and low-light areas of gardens where the humidity is raised; obviously countering these grow room conditions will slow the spread but it won't truly eliminate the fugus from the plants.

The same is true for sulphur applications; be it from a sulphur burner or from a solution such as Safer's Defender. Sulphur will prevent the growth of PM where it is present on the leaf, but the PM still exists within the plant.... not to mention sulphur applications negatively affect the taste of the final product; it seems to concentrate on the resins and an experienced or trained palate will always be able to tell if there was sulphur applied to the plants from how the hash smokes. I don't recommend using sulphur on vegging for flower or flowering plants

There is a product called Meltatox that is designed for application on ornamentals which gets into the plant and actually kills the PM. You should not spray this on plants that are going to be put into flower, or are in flowering. However, IMO it can safely be used to treat your veg state plants to eliminate the PM from your stock. I would suggest waiting at least 4 weeks before taking clones to be put into a veg/flower cycle.

Of course the MSDS is available online and anyone considering using the product should completely read the label instructions to inform themselves about the factors involved, how to properly spray and what precautions to take, the product half-life, etc before considering using.

It does work IME, and can be used as a part of a integrated approach that not only deals with eliminating all traces of spores from the growroom, but also removing the fungus from the plants themselves. Having either infected plants OR a spore infected growroom will ensure the problem persists as one will infect the other.

I would remove the plants, clean the room with industrial greenhouse cleaner, and use a sulphur burner before putting the plants back in the room. Then separately cut back the mothers and sterilize with Meltatox. If the plants are for consumption I'd then wait a month before getting back on schedule to take clones and veg out for the next crop... any remaining Meltatox in the plants would be negligible.

This product is not for everyone and is not safe to spray on flowering plants for consumption. I only recommend it's use to those that will use it responsibly and make themselves aware of the MSDS information available before choosing to use it.

-Chimera"

just for the record, I'm not chimera.

 

[ButteredIt]

wow. nevermind. found it right here.

this thread is all you need.

http://icmag.com/ic/showthread.php?t=129670

 

[dmt]

fuck man, west coast was same thing this year, never seen a bloom like this in 15 years. everyone complaining. i find the trick is avoid n overdose at any cost, get plants as big and vigorus as possible(no stress) and immune systems can keep it at bay. keep your humidity down and brezze a blowin. if growth is in the shade and not being utiklized, scrap it.

i gave a pm infected(not showing) clone to a buddy that drove it to winnipeg and has rocked it 2 years now, no pm there with it. i know that it is an internal ailment with powder symptoms. kushes are so suseptable, no pm in afghanistan i guess so lower immunity.

another option is grow a strain thats more resistant, it helps fersher. i know clean clean and clean is essential for prevention

im was feelin the outbreak too bro, d