My faithful cd-6 went out on me after over 10 years of faithful service so I had no co2 enrichment for the first 30 days of 12/12.I grow in an 8 by 8 room with 3 1K vertizontals and a 12.500 room window unit.The unit has a fresh air intake which is like uncovering a small hole.I've been growing for 15 years in this same room,and I know where a plant should be at a certain stage.I know these 12 cindy and Apollo's have had no negative issues from it that I can see.None at all.I know the plants make co2 during lights off and just being in the room your breath creates more.I never even considered running this room without co2 enrichment and my unit should be ready soon,but I don't see co2 as being a limiting factor when growing in my "sealed" room