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What is your medium? Check for a bacteria / fungus attack. I am a pretty good grower but I have fucked up so many clones it is embarrassing. Most of the time it is bad bacteria. I use rapid rooters now, I know they are apparently inoculated with goodies but I often add extra tricoderma or just dunk em in SM 90.
Swelling can be a good thing, but most of my very successful runs (90%+) stems dont change much, the roots just pop from the rooters.