High Grade CANNABIS BIBLIOGRAPHY SORTED AND ALPHABETIZED BY SUBJECT

[FellaAndrene]

Question for @Sam_Skunkman - Have you (or anyone you know) ever bioassayed cannabisativine and/or the other lactam based alkaloids in Cannabis?

I was browsing through ElSohly's works, and it happened to me that cannabisativine's molecular structure could have some affinity to other receptors than the CB1 and CB2.

Running it through Swiss Target Prediction's database returned results for possible interaction with kappa opioid (salvinorin A target) and 5-HT2A (classical psychedelic) receptors.

I'm not that well versed in 5-HT2A pharmacophore, but the receptors certainly are very accepting towards a wide variety of different compounds (from piperazines to phenethylamines to lysergides to efavirenz).


Can you send me the reference of the El Sohly paper, as well as the paper the image is from?
-SamS

 

[chilliwilli]

Histochemical Evidence for Nitrogen-Transfer Endosymbiosis in Non-Photosynthetic Cells of Leaves and Inflorescence Bracts of Angiosperms​

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220352/

https://doi.org/10.3390/biology11060876

They found n fixing bacteria in different plant cells. N transfer was also observed and was most likely in glandular trichomes.
"Trichome chemistry is hypothesized to function to scavenge oxygen around bacteria to facilitate nitrogen fixation."

I have the paper, I will add to the BIB
-SamS

 

[Deleted user 97766655]

https://doi.org/10.1111/nph.14107

Found this interesting for the Monopteros process and use of dex.

 

[acespicoli]

My health is up & down now I am on oxygen all day as my blood oxygen levels are so low. My advice to all is DO NOT GET OLD. I will be 75 this month. I am a happy guy but my health sucks the last 2 years.

Im a July baby as well, it crossed my mind to check on you last couple days. Been awhile since you posted I know life can be tough at times... so I thought id check in and send get well wishes
Hope this finds you doing well!

Various Articles & a few below that are interesting, hope everyone enjoys them!
Best >>>

Sci Adv. 2021 Jul; 7(29): eabg2286.
Published online 2021 Jul 16. doi: 10.1126/sciadv.abg2286
PMCID: PMC8284894
PMID: 34272249

Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa​

(This one is interesting to me due to basal drug types)

Basal (phylogenetics) - Wikipedia

en.wikipedia.org

I have and will add to the BIB-SamS

Plants 2023, 12(23), 3927; https://doi.org/10.3390/plants12233927

Naturally Occurring Triploidy in Cannabis​

(this article has some details and stats on natural well self explanatory... mutants)

Front. Plant Sci., 24 June 2020
Sec. Plant Systematics and Evolution
Volume 11 - 2020 | https://doi.org/10.3389/fpls.2020.00718

I have and will add to Bib -SamS

Hermaphroditism in Marijuana (Cannabis sativa L.) Inflorescences – Impact on Floral Morphology, Seed Formation, Progeny Sex Ratios, and Genetic Variation​

Dioecy - Wikipedia

en.wikipedia.org

Speciation - Wikipedia

en.wikipedia.org

BMC Genomics. 2018; 19: 156.
Published online 2018 Feb 21. doi: 10.1186/s12864-018-4494-3
PMCID: PMC5822635
PMID: 29466945

I have and will add to BIB-SamS

Diversity and evolution of the repetitive genomic content in Cannabis sativa​

Genome Biol Evol. 2021 Aug; 13(8): evab130.
Published online 2021 Jun 8. doi: 10.1093/gbe/evab130
PMCID: PMC8521752
PMID: 34100927

I have and will add to BIB-SamS

Origin and Evolution of the Cannabinoid Oxidocyclase Gene Family​

I have and will add to BIB-SamS

Plants 2019, 8(11), 496; https://doi.org/10.3390/plants8110496

Highly Predictive Genetic Markers Distinguish​

Drug-Type from Fiber-Type Cannabis sativa L​

I have and will add to BIB-SamS

Sire Lines & "Y" They Matter

Been interested in this topic for awhile now, maybe some others are as well? Questions why is cannabis important to us? Which genes are sex linked ? What are the current and future implications of culling males and hermaphrodites ? Is saving only female plants degrading the varieties and whole...

www.icmag.com

This chart represents the Illumina sequence coverage over the Bt/Bd allele. These are the three regions in the cannabis genome that impact THCA, CBDA, CBGA production. Coverage over the Active CBDAS gene is highly correlated with Type II and Type III plants as described by Etienne de Meijer. Coverage over the THCA gene is highly correlated with Type I and Type II plants but is anti-correlated with Type III plants. Type I plants require coverage over the inactive CBDA loci and no coverage over the Active CBDA gene. Lack of coverage over the Active CBDA and Active THCA allele are presumed to be Type IV plants (CBGA dominant). While deletions of entire THCAS and CBDAS genes are the most common Bt:Bd alleles observed, it is possible to have plants with these genes where functional expression of the enzyme is disrupted by deactivating point mutations (Kojoma et al. 2006).

Haze | Kannapedia

kannapedia.net

I have this and will add to BIB-SamS​

Some people mentioned you were working on collecting white papers, some of my favorite here.
Hope everyone finds them useful
I have and will add to BIB-SamS

 

[acespicoli]

Keeping it interesting in Kerala bagseed today all types broad to narrow who knows where its from

https://drive.google.com/file/d/1EQS2w3Yj5mVdVT3kE3sDU_1Byww-wPDM/view?usp=sharing

Report of the Indian Hemp Drugs Commission, 1894-1895 - Medicine - Drugs - Medical History of British India - National Library of Scotland

^ Maybe leave this here ? A little historical, but maybe in good company for a throw back Thursday
Good to see you back!!! Thanks for reading thru the last submission,

The Inheritance of Chemical Phenotype in Cannabis sativa L.​

Etienne P M de Meijer, Manuela Bagatta, Andrea Carboni, Paola Crucitti, V M Cristiana Moliterni, Paolo Ranalli, Giuseppe Mandolino
Author Notes
Genetics, Volume 163, Issue 1, 1 January 2003, Pages 335–346, https://doi.org/10.1093/genetics/163.1.335
Older study you may already have

Front. Plant Sci., 20 December 2018
Sec. Crop and Product Physiology
Volume 9 - 2018 | https://doi.org/10.3389/fpls.2018.01876

Frontiers | Latitudinal Adaptation and Genetic Insights Into the Origins of Cannabis sativa L.

Cannabis is one of the most important industrial crops distributed worldwide. However, the phylogeographic structure and domestication knowledge of this crop...

www.frontiersin.org

Sng et al. Journal of Cannabis Research (2024) 6:35 https://doi.org/10.1186/s42238-024-00246-8

Genome-wide identification of cannabinoid biosynthesis genes in non-drug type Cannabis (Cannabis sativa L.) cultivar - Journal of Cannabis Research

Background Cannabis sativa cultivars can be classified as marijuana or hemp, depending on its amount of the psychoactive cannabinoid Δ9‐tetrahydrocannabinolic acid (THCA). Hemp Cheungsam is a non-drug type Cannabis sativa that is characterized by low THCA content. However, the transcripts and...

jcannabisresearch.biomedcentral.com

Plants (Basel)
. 2019 Nov 12;8(11):496. doi: 10.3390/plants8110496

Highly Predictive Genetic Markers Distinguish Drug-Type from Fiber-Type Cannabis sativa L​

I added all 5 of these to my BIB and will add to the IC Cannabis Bib as soon as I am able to.
-SamS

 

[Green Zenit]

My health is up & down now I am on oxygen all day as my blood oxygen levels are so low. My advice to all is DO NOT GET OLD. I will be 75 this month. I am a happy guy but my health sucks the last 2 years.

Roger that! 🫡 message received: evoid continuous time exposure.
All the best for your health good sir!

 

[Sam_Skunkman]

I am still alive and hope I can add several hundreds of new papers to the IC BIB, it is quite hard for ne to keep up with all the new science papers being published, but I try. If anyone has new papers post them here with a link to the paper, the DOI if you have it, the title and authors and I will find it and post it when I can. All the best to all this is an exciting time for Cannabis breeders and Cannabis science, theCannabis world is changing fast.

 

[pipeline]

Thanks! Can't wait to see what kinds of research you have found! Acespicoli has been posting some in a couple discussion threads, we should try to organize them here.

Hope you get feeling better!

If what Acespicoli has articles I do not have in the IC BIB have him post them here so I can add them to the IC BIB.
-SamS

 

[CharlesU Farley]

I am still alive and hope I can add several hundreds of new papers to the IC BIB, it is quite hard for ne to keep up with all the new science papers being published, but I try. If anyone has new papers post them here with a link to the paper, the DOI if you have it, the title and authors and I will find it and post it when I can. All the best to all this is an exciting time for Cannabis breeders and Cannabis science, theCannabis world is changing fast.

I'm here in the US and am an RRT but have not practiced in decades. Did a bit of research on your condition, asked some old colleagues, told them you weren't here in the US.

They hope you are on at least one of these drugs... Nerandomilast, Saracatini., Saracatinibb.

Compared to what things were when I practiced, at least there's some treatment and hope for your condition now. As I always say, since I have decades of critical care experience, just take it a day at a time, do the best you can, and roll with it.

This was a project I've been working on:

How You Can Develop Cannabis To Do What You Want

TL; DR So CRISPR?

www.icmag.com

Write it up as an article and I will add it to the IC BIB.
-SamS

I got quite excited when I saw this journal article:

https://www.eurekalert.org/news-releases/1057451

DOI: https://doi.org/10.1093/hr/uhae161

"The study identifies CsMIKC1, a MIKC-type MADS-box transcription factor, as a pivotal regulator of inflorescence development in Cannabis sativa. Using CRISPR-Cas9 gene editing, the team examined how CsMIKC1 mutations and overexpression influence flower and grain production. Their findings offer fresh insights into the genetic architecture of inflorescence, underscoring the gene’s significant role in enhancing crop yields and presenting new avenues for genetic improvement."

I have this in my BIB at home I will be adding it when I can to the IC BIB
-SamS

This _is_ truly an exciting time in cannabis development. I would _never_ have thought this would have happened when I first lit one up back in the '60s.

 

[Sam_Skunkman]

Here are two that I will be adding to the IC BIB when I can

The Cannabis sativa Expression Atlas database

The Cannabis sativa Expression Atlas database

cannatlas.venanciogroup.uenf.br