Breakthrough discovery: cannabis compound 30 times stronger than THC

[G13Fan]

Hello ICMag , here is some interesting work being done in the cannabis research industry. Could be something this community could also begin to look into on a micro scale as opposed to a macro scale the big research industry can pump out.



Less than 50%
"
In a breakthrough for cannabis research scientists have discovered a cannabinoid in the cannabis plant that is

potentially 30 times stronger than THC.

Cannabis has over 400 known compounds in the plant, of which around 150 have been recognised as ‘cannabinoids’. The most commonly recognised cannabinoids are THC and CBD due to their pharmaceutical properties.
Now, in an attempt to define the phytocannabinoid profile that characterises medical cannabis, a group of Italian researchers from the University of Modena and Reggio Emilia, the University of Rome, the University of Campania, and the Institute of Nanotechnology in Lecce, have discovered two new compounds: THCP (tetrahydrocannabiphorol) and CBDP (cannabidiphorol).
The team of researchers describe in the report, published in the journal Nature, how they have isolated the two new cannabinoids, of which, THCP binds to the CB1 and CB2 receptors of human’s endocannbinoid system.
The scientists suggest that this cannabinoid is potentially 30 times more potent than THC – the known psychoactive component of cannabis.

Medical Cannabis Network spoke to team researcher, Cinzia Citti, from the Institute of Nanotechnology about the new discovery.
New cannabinoids: THCP and CBDP"

What can we learn from this now? The future appears bright for the evolution of the cannabis plant.


https://www.healtheuropa.eu/breakth...is-compound-30-times-stronger-than-thc/96329/

 

[White Beard]

Fascinating stuff, will watch for this.

Underscores the importance of keeping cannabis in the hands of the people, not the product-makers

 

[J-Icky]

well hopefully this will be looked at more. I’m sure it may prove to be why some strains that test in the high teens to low 20s are more enjoyable and get a lot of people “higher” than strains that test in the 30s.

 

[MAHA KALA]

exciting! I am sure there is still much to discover in miraculous cannabis resin.

 

[superpedro]

Nice find!

And published in "nature". Doesn't get more solid than that.

 

[TychoMonolyth]

Anyone know what strain they used? They called it CIN-RO.

 

[ESTERCHASER]

Anyone know what strain they used? They called it CIN-RO.

yeah its in your backyard clown

 

[HillBillyAlien]

soo one hit and your screwed

 

[Mikell]

"New research supports what old heads have been saying for decades"

 

[Ringodoggie]

I'll bet it won't get ME high. LOL

 

[Fitzera]

I wonder what level all this new high thc gear coming out will test at. Like I wonder if there is a correlation between thc and thcp levels. Or maybe it's been getting bred out in the chase for high thc levels and we dont know yet. Maybe that's why the old school strains used to be so potent, it used to have a higher level but it's been unintentionally bred out. Interesting to see what comes in the future

 

[G.O. Joe]

Maybe that's why the old school strains used to be so potent, it used to have a higher level but it's been unintentionally bred out. Interesting to see what comes in the future

Maybe people should hold off on guessing until this is found somewhere, anywhere else. The Italians didn't invent cannabinoid testing this year. Many odd cannabinoids have shown up in strains around the globe over the years.

 

[superpedro]

Maybe people should hold off on guessing until this is found somewhere, anywhere else. The Italians didn't invent cannabinoid testing this year. Many odd cannabinoids have shown up in strains around the globe over the years.

Here is what the science paper says:

It is reasonable to suppose that other cannabis varieties may contain even higher percentages of Δ9-THCP. It is also important to point out that there exists an astonishing variability of subject response to a cannabis-based therapy even with an equal Δ9-THC dose. It is therefore possible that the psychotropic effects are due to other extremely active phytocannabinoids such as Δ9-THCP. However, up to now nobody has ever searched for this potent phytocannabinoid in medicinal cannabis varieties. In our opinion, this compound should be included in the list of the main phytocannabinoids to be determined for a correct evaluation of the pharmacological effect of the cannabis extracts administered to patients. In fact, we believe that the discovery of an extremely potent THC-like phytocannabinoid may shed light on several pharmacological effects not ascribable solely to Δ9-THC.

 

[Guest]

OK for the rest of what will this benefit be to the folks who just like to grow their own? What is the real expected uses? Pain meds? Help with mental conditions ? Just clarify what the end goal is here if any? Is there a downside maybe from making something TOO strong that it causes problems ?

 

[superpedro]

OK for the rest of what will this benefit be to the folks who just like to grow their own? What is the real expected uses? Pain meds? Help with mental conditions ? Just clarify what the end goal is here if any? Is there a downside maybe from making something TOO strong that it causes problems ?

The thing is. We dont know how much THCP is in our plants already, if any.

What everybody agrees on, is that you can tell very little about how the mental effects will be from a cannabis strain, from the current list of cannabinoids we are looking at. This could be part of the explanation.

Wouldnt it be great if we one day understand the function of every cannabinoid and their effect on eachother, in order to enable us to find the perfect strain for an illness?

 

[JetLife175]

I hope it’s something that works in synergy with already established cannabinoids. This could possibly be the reason some plants are potent while others aren’t a la blackberry kush/purple punch etc.

This is really really interesting and finding new compounds like this only changes the game even more. Time to start sitting through all this vintage seed I’ve had stashed away for years it seems. Once proper testing and vetting happens with this it’s off to the races haha.

 

[englishrick]

Has anyone isomerized this chemical yet from other canna constituents?,,, it kinda sounds a lil like spice (nasty stuff)

The acitate is stronger than the delta 9,,,and thca can be made via delta9,, seems logical to convert to it

 

[CreatioExnihilo]

dont forget the acetate is both tricky to produce (requires a controlled chemical that is used to make heroin) and its also a class A drug in the UK!



The Adams scale only puts it a few times more potent than delta 9 w/w (but its 1.25 times heavier)