I tried it once.
I had this bag of super cheap supermarket soil laying around.
I flushed it and amended it with some good organic amendments.
(Atleast I thought I got the synthetics out of it...)
But no, I was wrong. I planted into it and after a short while I was running into issues. Know as Synthetic Death. It can happen when you mix synthetic and organic nutrients. My plants where clawing like crazy and were showing several other overfertilization/lockout issues.
I managed to pull the plants through. But the soil was pure crap also. After a few weeks it turned into this compact block which took forever to take water in...
I won't be doing that again.